BDH1 Antibody, Biotin conjugated (PACO25247)
- SKU:
- PACO25247
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Description
抗体名: | BDH1 Antibody, Biotin conjugated (PACO25247) |
抗体コード: | PACO25247 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human D-beta-hydroxybutyrate dehydrogenase, mitochondrial protein (47-343AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | D-beta-Hydroxybutyrate dehydrogenase mitochondria has been purified to apparent homogeneity. The membrane-bound enzyme is first released by phospholipase A digestion of the mitochondria. |
シノニム: | D-beta-hydroxybutyrate dehydrogenase, mitochondrial (EC 1.1.1.30) (3-hydroxybutyrate dehydrogenase) (BDH) (Short chain dehydrogenase/reductase family 9C member 1), BDH1, BDH SDR9C1 |
UniProt Protein Function: | BDH: a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008] |
UniProt Protein Details: | Protein type:Carbohydrate Metabolism - butanoate; Oxidoreductase; EC 1.1.1.30; Lipid Metabolism - synthesis and degradation of ketone bodies; Mitochondrial Chromosomal Location of Human Ortholog: 3q29 Cellular Component: nucleoplasm; mitochondrion; mitochondrial matrix; cytoplasm; mitochondrial inner membrane Molecular Function:3-hydroxybutyrate dehydrogenase activity; phospholipid binding Biological Process: response to drug; response to toxin; cellular lipid metabolic process; ketone body metabolic process; liver development; response to estradiol stimulus; response to insulin stimulus; response to starvation; response to cadmium ion; response to ethanol; ketone body catabolic process; ketone body biosynthetic process; brain development; response to nutrient; response to corticosterone stimulus |
NCBI Summary: | This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q02338 |
NCBI GenInfo Identifier: | 25108876 |
NCBI Gene ID: | 622 |
NCBI Accession: | Q02338.3 |
UniProt Secondary Accession: | Q02338,Q96ET1, Q9BRZ4, D3DXC0, |
UniProt Related Accession: | Q02338 |
Molecular Weight: | 343 |
NCBI Full Name: | D-beta-hydroxybutyrate dehydrogenase, mitochondrial |
NCBI Synonym Full Names: | 3-hydroxybutyrate dehydrogenase, type 1 |
NCBI Official Symbol: | BDH1 |
NCBI Official Synonym Symbols: | BDH; SDR9C1 |
NCBI Protein Information: | D-beta-hydroxybutyrate dehydrogenase, mitochondrial; (R)-3-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase (heart, mitochondrial); short chain dehydrogenase/reductase family 9C, member 1 |
UniProt Protein Name: | D-beta-hydroxybutyrate dehydrogenase, mitochondrial |
UniProt Synonym Protein Names: | 3-hydroxybutyrate dehydrogenase |
Protein Family: | (R,R)-butanediol dehydrogenase |
UniProt Gene Name: | BDH1 |
UniProt Entry Name: | BDH_HUMAN |