BCAS3 Antibody (PACO44610)
- SKU:
- PACO44610
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | BCAS3 Antibody (PACO44610) |
抗体コード: | PACO44610 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Breast carcinoma-amplified sequence 3 protein (689-928AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human brain tissue using PACO44610 at dilution of 1:100. |
バックグラウンド: | Plays a role in angiogenesis. Participates in the regulation of cell polarity and directional endothelial cell migration by mediating both the activation and recruitment of CDC42 and the reorganization of the actin cytoskeleton at the cell leading edge. Promotes filipodia formation (By similarity). Functions synergistically with PELP1 as a transcriptional coactivator of estrogen receptor-responsive genes. Stimulates histone acetyltransferase activity. Binds to chromatin. |
シノニム: | Breast carcinoma-amplified sequence 3 (GAOB1), BCAS3 |
UniProt Protein Function: | BCAS3: A chromosomal aberration involving BCAS3 has been found in some breast carcinoma cell lines. Translocation t(17;20)(q23;q13) with BCAS4. Belongs to the WD repeat BCAS3 family. 6 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Nuclear receptor co-regulator; Oncoprotein Chromosomal Location of Human Ortholog: 17q23 Cellular Component: intermediate filament cytoskeleton; cytoplasmic microtubule; leading edge; cytoplasm; nucleus Molecular Function:histone acetyltransferase binding; protein binding; histone binding; beta-tubulin binding; chromatin binding; transcription factor binding; nuclear hormone receptor binding Biological Process: response to starvation; vesicle-mediated transport; positive regulation of filopodium formation; positive regulation of catalytic activity; microtubule organizing center organization and biogenesis; transcription, DNA-dependent; negative regulation of focal adhesion formation; positive regulation of transcription from RNA polymerase II promoter; lumen formation; angiogenesis; Golgi organization and biogenesis |
UniProt Code: | Q9H6U6 |
NCBI GenInfo Identifier: | 313104248 |
NCBI Gene ID: | 54828 |
NCBI Accession: | Q9H6U6.3 |
UniProt Secondary Accession: | Q9H6U6,Q17RM0, Q6KF21, Q8IXI6, Q8NDR8, Q8TDL9, Q8TDM1 Q8WY55, Q9BVF0, Q9H957, Q9H9Y9, Q9NXP4, |
UniProt Related Accession: | Q9H6U6 |
Molecular Weight: | 928 |
NCBI Full Name: | Breast carcinoma-amplified sequence 3 |
NCBI Synonym Full Names: | breast carcinoma amplified sequence 3 |
NCBI Official Symbol: | BCAS3 |
NCBI Official Synonym Symbols: | MAAB; GAOB1 |
NCBI Protein Information: | breast carcinoma-amplified sequence 3; protein Maab1; BCAS4/BCAS3 fusion; metastasis associated antigen of breast cancer; breast carcinoma amplified sequence 4/3 fusion protein |
UniProt Protein Name: | Breast carcinoma-amplified sequence 3 |
UniProt Synonym Protein Names: | GAOB1 |
Protein Family: | Breast carcinoma-amplified sequence |
UniProt Gene Name: | BCAS3 |
UniProt Entry Name: | BCAS3_HUMAN |