BANP Antibody (PACO07978)
- SKU:
- PACO07978
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | BANP Antibody (PACO07978) |
抗体コード: | PACO07978 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human BANP |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | BTG3 associated nuclear protein;BANP;BEND1;DKFZp761H172;FLJ10177;FLJ20538;SMAR1;SMARBP1 ; |
UniProt Protein Function: | BANP: Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest. Belongs to the BANP/SMAR1 family. 6 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Tumor suppressor Chromosomal Location of Human Ortholog: 16q24 Cellular Component: nucleoplasm Molecular Function:protein binding; DNA binding; p53 binding Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; multicellular organismal development; chromatin modification; negative regulation of protein catabolic process; cell cycle |
NCBI Summary: | This gene encodes a protein that binds to matrix attachment regions. The protein forms a complex with p53 and negatively regulates p53 transcription, and functions as a tumor suppressor and cell cycle regulator. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010] |
UniProt Code: | Q8N9N5 |
NCBI GenInfo Identifier: | 308153628 |
NCBI Gene ID: | 54971 |
NCBI Accession: | Q8N9N5.3 |
UniProt Related Accession: | Q8N9N5 |
Molecular Weight: | |
NCBI Full Name: | Protein BANP |
NCBI Synonym Full Names: | BTG3 associated nuclear protein |
NCBI Official Symbol: | BANP |
NCBI Official Synonym Symbols: | BEND1; SMAR1; SMARBP1 |
NCBI Protein Information: | protein BANP |
UniProt Protein Name: | Protein BANP |
UniProt Synonym Protein Names: | BEN domain-containing protein 1; Btg3-associated nuclear protein; Scaffold/matrix-associated region-1-binding protein |
Protein Family: | Protein |
UniProt Gene Name: | BANP |
UniProt Entry Name: | BANP_HUMAN |