ATP2A3 Antibody (PACO20433)
- SKU:
- PACO20433
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ATP2A3 Antibody (PACO20433) |
抗体コード: | PACO20433 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthetic peptide of human ATP2A3 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20433(ATP2A3 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction. Alternative splicing results in multiple transcript variants encoding different isoforms. |
シノニム: | ATPase, Ca++ transporting, ubiquitous |
UniProt Protein Function: | ATP2A3: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports calcium ions from the cytosol into the sarcoplasmic/endoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily. 7 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Hydrolase; Endoplasmic reticulum; Transporter; Transporter, ion channel; EC 3.6.3.8; Membrane protein, integral Chromosomal Location of Human Ortholog: 17p13.3 Cellular Component: endoplasmic reticulum membrane; sarcoplasmic reticulum membrane; nuclear membrane; sarcoplasmic reticulum; endoplasmic reticulum; integral to membrane Molecular Function:calcium-transporting ATPase activity; metal ion binding; ATP binding Biological Process: transport; metabolic process; calcium ion transport; blood coagulation; transmembrane transport |
NCBI Summary: | This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q93084 |
NCBI GenInfo Identifier: | 19864659 |
NCBI Gene ID: | 489 |
NCBI Accession: | Q93084.2 |
UniProt Related Accession: | Q93084 |
Molecular Weight: | |
NCBI Full Name: | Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 |
NCBI Synonym Full Names: | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 |
NCBI Official Symbol: | ATP2A3 |
NCBI Official Synonym Symbols: | SERCA3 |
NCBI Protein Information: | sarcoplasmic/endoplasmic reticulum calcium ATPase 3 |
UniProt Protein Name: | Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 |
UniProt Synonym Protein Names: | Calcium pump 3 |
Protein Family: | Sarcoplasmic/endoplasmic reticulum calcium ATPase |
UniProt Gene Name: | ATP2A3 |
UniProt Entry Name: | AT2A3_HUMAN |
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