ATG16L1 Antibody (PACO07901)
- SKU:
- PACO07901
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ATG16L1 Antibody (PACO07901) |
抗体コード: | PACO07901 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human ATG16L1 |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | ATG16 autophagy related 16-like 1 (S. cerevisiae);ATG16L1;APG16L;ATG16L;FLJ00045;FLJ10035;FLJ10828;FLJ22677;IBD10;WDR30 ; |
UniProt Protein Function: | ATG16L1: Plays an essential role in autophagy. Homooligomer. Interacts with ATG5. Part of either the minor and major complexes respectively composed of 4 sets of ATG12-ATG5 and ATG16L1 (400 kDa) or 8 sets of ATG12-ATG5 and ATG16L1 (800 kDa). Belongs to the WD repeat ATG16 family. 5 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, peripheral; Adaptor/scaffold; Autophagy Chromosomal Location of Human Ortholog: 2q37.1 Cellular Component: autophagic vacuole; axoneme; cytosol Molecular Function:identical protein binding; protein binding; small conjugating protein ligase activity Biological Process: autophagic vacuole formation; macroautophagy Disease: Inflammatory Bowel Disease 10 |
NCBI Summary: | The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2010] |
UniProt Code: | Q676U5 |
NCBI GenInfo Identifier: | 62510482 |
NCBI Gene ID: | 55054 |
NCBI Accession: | Q676U5.2 |
UniProt Secondary Accession: | Q676U5,Q6IPN1, Q6UXW4, Q6ZVZ5, Q8NCY2, Q96JV5, Q9H619 A3EXK9, A3EXL0, B6ZDH0, |
UniProt Related Accession: | Q676U5 |
Molecular Weight: | 49,486 Da |
NCBI Full Name: | Autophagy-related protein 16-1 |
NCBI Synonym Full Names: | autophagy related 16 like 1 |
NCBI Official Symbol: | ATG16L1 |
NCBI Official Synonym Symbols: | IBD10; WDR30; APG16L; ATG16A; ATG16L |
NCBI Protein Information: | autophagy-related protein 16-1 |
UniProt Protein Name: | Autophagy-related protein 16-1 |
UniProt Synonym Protein Names: | APG16-like 1 |
Protein Family: | Autophagy-related protein |
UniProt Gene Name: | ATG16L1 |
UniProt Entry Name: | A16L1_HUMAN |