ATCAY Antibody (PACO07894)
- SKU:
- PACO07894
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ATCAY Antibody (PACO07894) |
抗体コード: | PACO07894 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human ATCAY |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | ataxia, cerebellar, Cayman type;ATCAY;BNIP-H;CLAC;KIAA1872 ; |
UniProt Protein Function: | ATCAY: Functions in the development of neural tissues, particularly the postnatal maturation of the cerebellar cortex. May play a role in neurotransmission through regulation of glutaminase/GLS, an enzyme responsible for the production in neurons of the glutamate neurotransmitter. Alternatively, may regulate the localization of mitochondria within axons and dendrites. Defects in ATCAY are the cause of cerebellar ataxia, cayman type (ATCAY). ATCAY is found in a population isolate on Grand Cayman Island and causes a marked psychomotor retardation and prominent nonprogressive cerebellar dysfunction including nystagmus, intention tremor, dysarthria, and wide-based ataxic gait. Hypotonia is present from early childhood. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: neuron projection; mitochondrion; axon; cytoplasm; dendrite; mitochondrial membrane; synapse; cell junction Molecular Function:protein binding; kinesin binding Biological Process: regulation of protein localization; apoptosis; transport; neurite development; mitochondrion distribution Disease: Cerebellar Ataxia, Cayman Type |
NCBI Summary: | This gene encodes a neuron-restricted protein that contains a CRAL-TRIO motif common to proteins that bind small lipophilic molecules. Mutations in this gene are associated with cerebellar ataxia, Cayman type. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q86WG3 |
NCBI GenInfo Identifier: | 29336043 |
NCBI Gene ID: | 85300 |
NCBI Accession: | NP_149053.1 |
UniProt Secondary Accession: | Q86WG3,Q8NAQ2, Q8TAQ3, Q96HC6, Q96JF5, |
UniProt Related Accession: | Q86WG3 |
Molecular Weight: | 42,821 Da |
NCBI Full Name: | caytaxin |
NCBI Synonym Full Names: | ataxia, cerebellar, Cayman type |
NCBI Official Symbol: | ATCAY |
NCBI Official Synonym Symbols: | CLAC; BNIP-H |
NCBI Protein Information: | caytaxin; Cayman ataxia; BNIP-2-homolgy; BNIP-2-homology; ataxia cayman type protein |
UniProt Protein Name: | Caytaxin |
UniProt Synonym Protein Names: | Ataxia cayman type protein; BNIP-2-homology; BNIP-H |
Protein Family: | Caytaxin |
UniProt Gene Name: | ATCAY |
UniProt Entry Name: | ATCAY_HUMAN |