ASMT Antibody, HRP conjugated (PACO56729)
- SKU:
- PACO56729
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | ASMT Antibody, HRP conjugated (PACO56729) |
抗体コード: | PACO56729 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Acetylserotonin O-methyltransferase protein (221-316AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Isoform 1 catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). Isoform 2 and isoform 3 lack enzyme activity. |
シノニム: | Acetylserotonin O-methyltransferase (EC 2.1.1.4) (Hydroxyindole O-methyltransferase) (HIOMT), ASMT |
UniProt Protein Function: | ASMT: Produces melatonin (N-acetyl-5-methoxytryptamine) from N-acetylserotonin. Belongs to the methyltransferase superfamily. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Amino Acid Metabolism - tryptophan; EC 2.1.1.4; Methyltransferase Chromosomal Location of Human Ortholog: Xp22.33 and Yp11.2 Cellular Component: cytosol Molecular Function:acetylserotonin O-methyltransferase activity; identical protein binding; O-methyltransferase activity; protein homodimerization activity; S-methyltransferase activity Biological Process: indolalkylamine biosynthetic process; melatonin biosynthetic process; translation |
NCBI Summary: | This gene belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2010] |
UniProt Code: | P46597 |
NCBI GenInfo Identifier: | 1170276 |
NCBI Gene ID: | 438 |
NCBI Accession: | P46597.1 |
UniProt Secondary Accession: | P46597,Q16598, Q5JQ72, Q5JQ73, B2RC33, |
UniProt Related Accession: | P46597 |
Molecular Weight: | Calculated MW: 33kDa/38kDa/41kDaObserved MW: 52kDa |
NCBI Full Name: | Acetylserotonin O-methyltransferase |
NCBI Synonym Full Names: | acetylserotonin O-methyltransferase |
NCBI Official Symbol: | ASMT |
NCBI Official Synonym Symbols: | ASMTY; HIOMT; HIOMTY |
NCBI Protein Information: | acetylserotonin O-methyltransferase |
UniProt Protein Name: | Acetylserotonin O-methyltransferase |
UniProt Synonym Protein Names: | Hydroxyindole O-methyltransferase; HIOMT |
Protein Family: | Acetylserotonin O-methyltransferase |
UniProt Gene Name: | ASMT |