APOBEC2 Antibody (PACO19122)
- SKU:
- PACO19122
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | APOBEC2 Antibody (PACO19122) |
抗体コード: | PACO19122 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | ELISA:1:1000-1:2000, WB:1:200-1:1000 |
反応性: | Human, Mouse |
免疫原: | Synthetic peptide of human APOBEC2 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Mouse muscle tissue, Mouse skin tissue, Primary antibody: PACO19122(APOBEC2 Antibody) at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds. |
バックグラウンド: | Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 (APOBEC2) is a 224 amino acid, protein that belongs to the cytidine and deoxycytidylate deaminase family. Expressed exclusively in heart and skeletal muscle, APOBEC2 is thought to be a probable C (cytidine) to U (uridine) editing enzyme. However, unlike other members of the family, such as APOBEC1, which mediates the editing of apolipoprotein (apo) B mRNA, APOBEC2 does not display any detectable apoB mRNA editing activity. Also, APOBEC2 has been shown to have low, but definite, intrinsic cytidine deaminase activity. |
シノニム: | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
UniProt Protein Function: | APOBEC2: Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation. Belongs to the cytidine and deoxycytidylate deaminase family. |
UniProt Protein Details: | Protein type:EC 3.5.4.-; Hydrolase; RNA-binding Chromosomal Location of Human Ortholog: 6p21 Molecular Function:zinc ion binding; RNA binding; cytidine deaminase activity Biological Process: mRNA modification; cytidine deamination; mRNA processing |
UniProt Code: | Q9Y235 |
NCBI GenInfo Identifier: | 23396446 |
NCBI Gene ID: | 10930 |
NCBI Accession: | Q9Y235.1 |
UniProt Related Accession: | Q9Y235 |
Molecular Weight: | |
NCBI Full Name: | C-> |
NCBI Synonym Full Names: | apolipoprotein B mRNA editing enzyme catalytic subunit 2 |
NCBI Official Symbol: | APOBEC2 |
NCBI Official Synonym Symbols: | ARP1; ARCD1 |
NCBI Protein Information: | C->U-editing enzyme APOBEC-2 |
UniProt Protein Name: | Probable C->U-editing enzyme APOBEC-2 |
Protein Family: | C->U-editing enzyme |
UniProt Gene Name: | APOBEC2 |
UniProt Entry Name: | ABEC2_HUMAN |