APEH Antibody, FITC conjugated (PACO24970)
- SKU:
- PACO24970
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | APEH Antibody, FITC conjugated (PACO24970) |
抗体コード: | PACO24970 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Acylamino-acid, releasing enzyme protein (201-500AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid, and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser. |
シノニム: | Acylamino-acid, releasing enzyme (AARE) (EC 3.4.19.1) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase) (Oxidized protein hydrolase) (OPH), APEH, D3F15S2 D3S48E DNF15S2 |
UniProt Protein Function: | APEH: This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N- acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser. Belongs to the peptidase S9C family. |
UniProt Protein Details: | Protein type:Protease; EC 3.4.19.1 Chromosomal Location of Human Ortholog: 3p21.31 Cellular Component: nuclear membrane; cytoplasm Molecular Function:omega peptidase activity; serine-type endopeptidase activity Biological Process: beta-amyloid metabolic process; proteolysis |
NCBI Summary: | This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma. [provided by RefSeq, Jul 2008] |
UniProt Code: | P13798 |
NCBI GenInfo Identifier: | 38258902 |
NCBI Gene ID: | 327 |
NCBI Accession: | P13798.4 |
UniProt Secondary Accession: | P13798,Q9BQ33, Q9P0Y2, |
UniProt Related Accession: | P13798 |
Molecular Weight: | 732 |
NCBI Full Name: | Acylamino-acid-releasing enzyme |
NCBI Synonym Full Names: | acylaminoacyl-peptide hydrolase |
NCBI Official Symbol: | APEH |
NCBI Official Synonym Symbols: | APH; OPH; AARE; ACPH; D3S48E; D3F15S2; DNF15S2 |
NCBI Protein Information: | acylamino-acid-releasing enzyme; acyl-peptide hydrolase; acylaminoacyl-peptidase; oxidized protein hydrolase; N-acylaminoacyl-peptide hydrolase |
UniProt Protein Name: | Acylamino-acid-releasing enzyme |
UniProt Synonym Protein Names: | Acyl-peptide hydrolase; APH; Acylaminoacyl-peptidase; Oxidized protein hydrolase; OPH |
Protein Family: | Acylamino-acid-releasing enzyme |
UniProt Gene Name: | APEH |
UniProt Entry Name: | ACPH_HUMAN |