Anti-TMEM27 Antibody (CAB12715)
- SKU:
- CAB12715
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-TMEM27 Antibody |
抗体コード: | CAB12715 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-222 of human TMEM27 (NP_065716.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Mouse, Rat |
ポジティブサンプル: | Mouse kidney, Mouse pancreas, Rat kidney |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-222 of human TMEM27 (NP_065716.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MLWL LFFL VTAI HAEL CQPG AENA FKVR LSIR TALG DKAY AWDT NEEY LFKA MVAF SMRK VPNR EATE ISHV LLCN VTQR VSFW FVVT DPSK NHTL PAVE VQSA IRMN KNRI NNAF FLND QTLE FLKI PSTL APPM DPSV PIWI IIFG VIFC IIIV AIAL LILS GIWQ RRRK NKEP SEVD DAED KCEN MITI ENGI PSDP LDMK GGHI NDAF MTED ERLT PL |
遺伝子ID: | 57393 |
Uniprot: | Q9HBJ8 |
セルラーロケーション: | Membrane, Single-pass type I membrane protein |
計算された分子量: | 25kDa |
観察された分子量: | 29kDa |
同義語: | TMEM27, NX-17, NX17 |
バックグラウンド: | This gene encodes a type 1 transmembrane protein that is important for trafficking amino acid transporters to the apical brush border of proximal tubules. The encoded protein binds to amino acid transporters and regulates their expression on the plasma membrane. It also plays a role in controlling insulin exocytosis by regulating formation of the SNARE (soluble N-ethylmaleimide-sensitive-factor attachment protein receptor) complex in pancreatic beta cells. The extracellular domain of the encoded protein may be cleaved and shed from the plasma membrane specifically in pancreatic beta cells. |
UniProt Protein Function: | TMEM27: Regulator of SNARE complex function. Stimulator of beta cell replication. Belongs to the TMEM27 family. |
UniProt Protein Details: | Protein type:Cell surface; Membrane protein, integral Chromosomal Location of Human Ortholog: Xp22 Cellular Component: brush border membrane; cytoplasm; integral to membrane Molecular Function:peptidyl-dipeptidase activity; protein binding; metallopeptidase activity Biological Process: positive regulation of calcium ion-dependent exocytosis; proteolysis; positive regulation of amino acid transport |
NCBI Summary: | This gene encodes a type 1 transmembrane protein that is important for trafficking amino acid transporters to the apical brush border of proximal tubules. The encoded protein binds to amino acid transporters and regulates their expression on the plasma membrane. It also plays a role in controlling insulin exocytosis by regulating formation of the SNARE (soluble N-ethylmaleimide-sensitive-factor attachment protein receptor) complex in pancreatic beta cells. The extracellular domain of the encoded protein may be cleaved and shed from the plasma membrane specifically in pancreatic beta cells. [provided by RefSeq, Jun 2013] |
UniProt Code: | Q9HBJ8 |
NCBI GenInfo Identifier: | 74734254 |
NCBI Gene ID: | 57393 |
NCBI Accession: | Q9HBJ8.1 |
UniProt Secondary Accession: | Q9HBJ8,Q6UW07, B2R9M1, |
UniProt Related Accession: | Q9HBJ8 |
Molecular Weight: | 222 |
NCBI Full Name: | Collectrin |
NCBI Synonym Full Names: | transmembrane protein 27 |
NCBI Official Symbol: | TMEM27 |
NCBI Official Synonym Symbols: | NX17; NX-17 |
NCBI Protein Information: | collectrin; kidney-specific membrane protein |
UniProt Protein Name: | Collectrin |
UniProt Synonym Protein Names: | Transmembrane protein 27 |
Protein Family: | Collectrin |
UniProt Gene Name: | TMEM27 |
UniProt Entry Name: | TMM27_HUMAN |
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