Anti-STX4 Antibody (RACO0559)
- SKU:
- RACO0559
- Product type:
- Recombinant Antibody
- Reactivity:
- Human
- Host Species:
- Human
- Isotype:
- IgG
- Application:
- WB
- Application:
- ELISA
- Conjugation:
- Unconjugated
Description
商品名: | STX4 Antibody |
Product SKU: | RACO0559 |
サイズ: | 50ul |
宿主種: | Homo sapiens (Human) |
申し込み: | ELISA, WB |
推奨される希釈: | WB:1:500-1:5000 |
反応性: | Human |
免疫原: | A synthesized peptide derived from human Syntaxin 4 |
憲法: | Liquid |
ストレージバッファ: | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
精製方法: | Affinity-chromatography |
抗体のクローン性: | Monoclonal |
アイソタイプ: | Rabbit IgG |
Conjugate: | Non-conjugated |
バックグラウンド: | Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity). May also play a role in docking of synaptic vesicles at presynaptic active zones. |
シノニム: | Syntaxin-4 (Renal carcinoma antigen NY-REN-31), STX4, STX4A |
Western Blot. Positive WB detected in 293 whole cell lysate Jurkat whole cell lysate K562 whole cell lysate Hela whole cell lysate HL-60 whole cell lysate A375 whole cell lysate MCF-7 whole cell lysate All lanes Syntaxin 4 antibody at 1:1000. Secondary. Goat polyclonal to rabbit IgG at 1:50000 dilution. Predicted band size: 35, 34 kDa. Observed band size: 35 kDa. |
UniProt Protein Function: | STX4: a protein of the syntaxin/epimorphin family. Contains 1 t-SNARE coiled-coil homology domain. Potentially involved in docking of synaptic vesicles at presynaptic active zones. Interacts with SNAP23 and SNAP25BP. Found in a complex with VAMP8 and SNAP23 in pancreas. |
UniProt Protein Details: | Protein type:Vesicle; Membrane protein, integral Chromosomal Location of Human Ortholog: 16p11.2 Cellular Component: extracellular space; specific granule; cell surface; lateral loop; basolateral plasma membrane; integral to membrane; dendritic spine; trans-Golgi network; cytosol; SNARE complex; synaptic vesicle; membrane; perinuclear region of cytoplasm; lamellipodium; plasma membrane; vacuole; synapse; intracellular; endosome Molecular Function:sphingomyelin phosphodiesterase activator activity; SNAP receptor activity; SNARE binding; protein binding Biological Process: positive regulation of catalytic activity; platelet activation; positive regulation of cell adhesion; organelle fusion; positive regulation of eosinophil degranulation; positive regulation of chemotaxis; positive regulation of immunoglobulin secretion; synaptic vesicle fusion to presynaptic membrane; regulation of exocytosis; intracellular protein transport; response to hydroperoxide; vesicle docking; positive regulation of cell proliferation; post-Golgi vesicle-mediated transport; blood coagulation; positive regulation of cell migration |
UniProt Code: | Q12846 |
NCBI GenInfo Identifier: | 3041737 |
NCBI Gene ID: | 6810 |
NCBI Accession: | Q12846.2 |
UniProt Secondary Accession: | Q12846,Q3SWZ3, P70452, Q08850, |
UniProt Related Accession: | Q12846 |
Molecular Weight: | 34180 |
NCBI Full Name: | Syntaxin-4 |
NCBI Synonym Full Names: | syntaxin 4 |
NCBI Official Symbol: | STX4 |
NCBI Official Synonym Symbols: | STX4A; p35-2 |
NCBI Protein Information: | syntaxin-4 |
UniProt Protein Name: | Syntaxin-4 |
UniProt Synonym Protein Names: | Renal carcinoma antigen NY-REN-31 |
UniProt Gene Name: | STX4 |
UniProt Entry Name: | STX4_HUMAN |