Anti-PLG Antibody (CAB3320)
- SKU:
- CAB3320
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cardiovascular
Frequently bought together:
Description
抗体名: | Anti-PLG Antibody |
抗体コード: | CAB3320 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human PLG (NP_000292.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | Human plasma, Mouse serum, Rat serum |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human PLG (NP_000292.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | EPLD DYVN TQGA SLFS VTKK QLGA GSIE ECAA KCEE DEEF TCRA FQYH SKEQ QCVI MAEN RKSS IIIR MRDV VLFE KKVY LSEC KTGN GKNY RGTM SKTK NGIT CQKW SSTS PHRP RFSP ATHP SEGL EENY CRNP DNDP QGPW CYTT DPEK RYDY CDIL ECEE ECMH CSGE NYDG KISK TMSG LECQ AWDS QSPH AHGY IPSK FPNK NLKK NYCR NPDR ELRP WCFT TDPN KRWE LCDI PRCT TPPP SSGP TYQC LKGT GENY RGNV AVTV SGHT CQHW S |
遺伝子ID: | 5340 |
Uniprot: | P00747 |
セルラーロケーション: | Secreted |
計算された分子量: | 90kDa |
観察された分子量: | 125kDa |
同義語: | PLG |
バックグラウンド: | The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene. |
UniProt Protein Function: | Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells. |
NCBI Summary: | The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009] |
UniProt Code: | P00747 |
NCBI GenInfo Identifier: | 130316 |
NCBI Gene ID: | 5340 |
NCBI Accession: | P00747.2 |
UniProt Secondary Accession: | P00747,Q15146, Q5TEH4, Q6PA00, |
UniProt Related Accession: | P00747 |
Molecular Weight: | 90,569 Da |
NCBI Full Name: | Plasminogen |
NCBI Synonym Full Names: | plasminogen |
NCBI Official Symbol: | PLG |
NCBI Protein Information: | plasminogen |
UniProt Protein Name: | Plasminogen |
Protein Family: | Plasminogen |
UniProt Gene Name: | PLG |
UniProt Entry Name: | PLMN_HUMAN |
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