Anti-Phospho-Rac1/Cdc42-S71 Antibody (CABP1018)
- SKU:
- CABP1018
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-Phospho-Rac1/Cdc42-S71 Antibody |
| 抗体コード: | CABP1018 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | A phospho specific peptide corresponding to residues surrounding S71 of human Rac1/Cdc42 |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | A-431 |
| 免疫原: | A phospho specific peptide corresponding to residues surrounding S71 of human Rac1/Cdc42 |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 998/5879 |
| Uniprot: | P60953/P63000 |
| セルラーロケーション: | |
| 計算された分子量: | 24kDa |
| 観察された分子量: | 24KDa |
 | Western blot - Phospho-Rac1/Cdc42-S71 Rabbit mAb (CABP1018) |
| 同義語: | CDC42Hs, G25K, TKS |
| バックグラウンド: | The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013] |
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