Anti-Phospho-PAK4/PAK5/PAK6-S474/S560/S602 Antibody (CABP1049)
- SKU:
- CABP1049
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
Frequently bought together:
Description
抗体名: | Anti-Phospho-PAK4/PAK5/PAK6-S474/S560/S602 Antibody |
抗体コード: | CABP1049 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A phospho specific peptide corresponding to residues surrounding S474 of human PAK4 |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | NIH/3T3, C6 |
免疫原: | A phospho specific peptide corresponding to residues surrounding S474 of human PAK4 |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 10298/57144/56924 |
Uniprot: | O96013(PAK4-Antigen), Q9P286(PAK5), Q9NQU5(PAK6) |
セルラーロケーション: | |
計算された分子量: | 64, 80, 75 kDa |
観察された分子量: | 64KDa/75KDa |
同義語: | |
バックグラウンド: | PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |