Anti-Phospho-NRF2-S40 Antibody (CABP1167)
- SKU:
- CABP1167
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
| 抗体名: | Anti-Phospho-NRF2-S40 Antibody |
| 抗体コード: | CABP1167 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | A phospho specific peptide corresponding to residues surrounding S40 of human NRF2 |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | NIH/3T3 |
| 免疫原: | A phospho specific peptide corresponding to residues surrounding S40 of human NRF2 |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 4780 |
| Uniprot: | Q16236 |
| セルラーロケーション: | Cytoplasm, Nucleus, cytosol |
| 計算された分子量: | 90kDa |
| 観察された分子量: | 65kDa |
 | Western blot - Phospho-NRF2-S40 Rabbit pAb (CABP1167) |
| 同義語: | HEBP1, NRF2 |
| バックグラウンド: | This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene. |
| UniProt Protein Function: | NRF2: a transcription factor that regulates basal expression and antioxidant induction of a transcription factor for NAD(P)H:quinone oxidoreductase-1 (NQO1) and other detoxifying genes. Targeted for proteasomal degradation by INrf2. Oxidative stress causes its phosphorylation and release from INrf2. |
| UniProt Protein Details: | Protein type:DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 2q31.2 Cellular Component: centrosome; cytoplasm; cytosol; nucleus; plasma membrane Molecular Function:DNA binding; protein binding; protein domain specific binding; transcription factor activity Biological Process: positive regulation of transcription from RNA polymerase II promoter; proteasomal ubiquitin-dependent protein catabolic process; proteasomal ubiquitin-independent protein catabolic process; protein ubiquitination; transcription from RNA polymerase II promoter; unfolded protein response |
| NCBI Summary: | This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene. [provided by RefSeq, Sep 2015] |
| UniProt Code: | Q16236 |
| NCBI GenInfo Identifier: | 25453452 |
| NCBI Gene ID: | 4780 |
| NCBI Accession: | Q16236.3 |
| UniProt Secondary Accession: | Q16236,Q53RW6, Q59HH2, Q96F71, B2RBU2, B4E338, E9PGJ7 |
| UniProt Related Accession: | Q16236 |
| Molecular Weight: | 65,356 Da |
| NCBI Full Name: | Nuclear factor erythroid 2-related factor 2 |
| NCBI Synonym Full Names: | nuclear factor, erythroid 2 like 2 |
| NCBI Official Symbol: | NFE2L2 |
| NCBI Official Synonym Symbols: | NRF2; HEBP1 |
| NCBI Protein Information: | nuclear factor erythroid 2-related factor 2 |
| UniProt Protein Name: | Nuclear factor erythroid 2-related factor 2 |
| UniProt Synonym Protein Names: | HEBP1; Nuclear factor, erythroid derived 2, like 2 |
| UniProt Gene Name: | NFE2L2 |
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