Anti-Phospho-HDAC4-S246/HDAC5-S259/HDAC9-S220 Antibody (CABP0280)
- SKU:
- CABP0280
- Product type:
- Antibody
- Application:
- WB
- Application:
- IHC
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-Phospho-HDAC4-S246/HDAC5-S259/HDAC9-S220 Antibody |
抗体コード: | CABP0280 |
抗体サイズ: | 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | A phospho specific peptide corresponding to residues surrounding S246 of human HDAC4 |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:1000 IHC 1:50 - 1:100 |
反応性: | Human |
ポジティブサンプル: | 293, 293+EGF |
免疫原: | A phospho specific peptide corresponding to residues surrounding S246 of human HDAC4 |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 9759/10014/9734 |
Uniprot: | P56524/Q9UQL6/Q9UKV0 |
セルラーロケーション: | |
計算された分子量: | 57-65kDa/97-122kDa |
観察された分子量: | 125kDa/140kDa |
同義語: | HDAC4/HDAC5/HDAC9 |
バックグラウンド: | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008] |