Anti-Phospho-FOXO1-S319 抗体 (CABP1090)

Anti-Phospho-FOXO1-S319 Antibody (CABP1090)

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SKU:

CABP1090

Product type:

Antibody

Reactivity:

Human

Reactivity:

Mouse

Reactivity:

Rat

Host Species:

Rabbit

Isotype:

IgG

Antibody Type:

Polyclonal Antibody

Research Area:

Cell Death

Description

Description

データシート安全性データシート

同義語:	FKH1, FKHR, FOXO1A, FOXO1
バックグラウンド:	This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. [provided by RefSeq, Jul 2008]

UniProt Protein Function:	FOXO1A: a transcription factor of the forkhead family. A central regulator of metabolism in several cell types. May play an important role in myogenic growth and differentiation, and in the regulation of lipolysis in adipocytes by controlling the expression of adipose triglyceride lipase (ATGL), the rate-limiting lipolytic enzyme. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. Contains 1 fork-head domain.
UniProt Protein Details:	Protein type:Nuclear receptor co-regulator; Oncoprotein; DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 13q14.1 Cellular Component: cytoplasm; cytosol; mitochondrion; nucleoplasm; nucleus Molecular Function:beta-catenin binding; chromatin binding; protein binding; protein phosphatase 2A binding; sequence-specific DNA binding; ubiquitin protein ligase binding Biological Process: anatomical structure morphogenesis; apoptosis; autophagy; blood vessel development; cell differentiation; cell glucose homeostasis; cellular response to insulin stimulus; cellular response to starvation; endocrine pancreas development; epidermal growth factor receptor signaling pathway; fat cell differentiation; fibroblast growth factor receptor signaling pathway; innate immune response; insulin receptor signaling pathway; negative regulation of apoptosis; negative regulation of fat cell differentiation; negative regulation of stress-activated MAPK cascade; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; nerve growth factor receptor signaling pathway; phosphoinositide-mediated signaling; positive regulation of apoptosis; positive regulation of autophagy; positive regulation of gluconeogenesis; positive regulation of protein catabolic process; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; protein amino acid acetylation; response to DNA damage stimulus; thermoregulation; transcription, DNA-dependent Disease: Rhabdomyosarcoma 2
NCBI Summary:	This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. [provided by RefSeq, Jul 2008]
UniProt Code:	Q12778
NCBI GenInfo Identifier:	116241368
NCBI Gene ID:	2308
NCBI Accession:	Q12778.2
UniProt Secondary Accession:	Q12778,O43523, Q5VYC7, Q6NSK6,
UniProt Related Accession:	Q12778
Molecular Weight:
NCBI Full Name:	Forkhead box protein O1
NCBI Synonym Full Names:	forkhead box O1
NCBI Official Symbol:	FOXO1
NCBI Official Synonym Symbols:	FKH1; FKHR; FOXO1A
NCBI Protein Information:	forkhead box protein O1
UniProt Protein Name:	Forkhead box protein O1
UniProt Synonym Protein Names:	Forkhead box protein O1A; Forkhead in rhabdomyosarcoma
Protein Family:	Foxo1-corepressor
UniProt Gene Name:	FOXO1
UniProt Entry Name:	FOXO1_HUMAN

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