Anti-PAFAH2 Antibody (CAB16941)
- SKU:
- CAB16941
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-PAFAH2 Antibody |
抗体コード: | CAB16941 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 260-350 of human PAFAH2 (NP_000428.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 260-350 of human PAFAH2 (NP_000428.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | AWMF PLER DFYP KARG PVFF INTE KFQT MESV NLMK KICA QHEQ SRII TVLG SVHR SQTD FAFV TGNL IGKF FSTE TRGS LDPY EGQE VMV |
遺伝子ID: | 5051 |
Uniprot: | Q99487 |
セルラーロケーション: | |
計算された分子量: | 44kDa |
観察された分子量: | Refer to figures |
同義語: | PAFAH2, HSD-PLA2 |
バックグラウンド: | This gene encodes platelet-activating factor acetylhydrolase isoform 2, a single-subunit intracellular enzyme that catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). However, this lipase exhibits a broader substrate specificity than simply platelet activating factor. Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist, and both are multi-subunit enzymes. Additionally, there is a single-subunit serum isoform of this enzyme. |
UniProt Protein Function: | PAFAH2: Has a marked selectivity for phospholipids with short acyl chains at the sn-2 position. May share a common physiologic function with the plasma-type enzyme. Belongs to the serine esterase family. |
UniProt Protein Details: | Protein type:Hydrolase; Lipid-binding; EC 3.1.1.47; Lipid Metabolism - ether lipid Chromosomal Location of Human Ortholog: 1p36 Molecular Function:phospholipid binding Biological Process: lipid metabolic process |
NCBI Summary: | This gene encodes platelet-activating factor acetylhydrolase isoform 2, a single-subunit intracellular enzyme that catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). However, this lipase exhibits a broader substrate specificity than simply platelet activating factor. Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist, and both are multi-subunit enzymes. Additionally, there is a single-subunit serum isoform of this enzyme. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q99487 |
NCBI GenInfo Identifier: | 6647691 |
NCBI Gene ID: | 5051 |
NCBI Accession: | Q99487.1 |
UniProt Secondary Accession: | Q99487,O15458, Q5SY02, D3DPK1, |
UniProt Related Accession: | Q99487 |
Molecular Weight: | 44,036 Da |
NCBI Full Name: | Platelet-activating factor acetylhydrolase 2, cytoplasmic |
NCBI Synonym Full Names: | platelet activating factor acetylhydrolase 2 |
NCBI Official Symbol: | PAFAH2 |
NCBI Official Synonym Symbols: | HSD-PLA2 |
NCBI Protein Information: | platelet-activating factor acetylhydrolase 2, cytoplasmic |
UniProt Protein Name: | Platelet-activating factor acetylhydrolase 2, cytoplasmic |
UniProt Synonym Protein Names: | Serine-dependent phospholipase A2; SD-PLA2; hSD-PLA2 |
Protein Family: | Platelet-activating factor acetylhydrolase |
UniProt Gene Name: | PAFAH2 |
UniProt Entry Name: | PAFA2_HUMAN |
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