Anti-MYOD1 Antibody (CAB0671)
- SKU:
- CAB0671
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Description
抗体名: | Anti-MYOD1 Antibody |
抗体コード: | CAB0671 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human MYOD1 (NP_002469.2). |
申し込み: | WB IF |
推奨希釈: | WB 1:500 - 1:1000 IF 1:20 - 1:50 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HeLa, HT-1080 |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human MYOD1 (NP_002469.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | LRNA IRYI EGLQ ALLR DQDA APPG AAAA FYAP GPLP PGRG GEHY SGDS DASS PRSN CSDG MMDY SGPP SGAR RRNC YEGA YYNE APSE PRPG KSAA VSSL D |
遺伝子ID: | 4654 |
Uniprot: | P15172 |
セルラーロケーション: | Nucleus |
計算された分子量: | 34kDa |
観察された分子量: | 40KDa |
同義語: | MYOD1, MYF3, MYOD, PUM, bHLHc1 |
バックグラウンド: | This gene encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis. |
UniProt Protein Function: | MyoD: a transcription factor of the basic helix-loop-helix family and the myogenic factors subfamily. Involved in muscle differentiation. Induces fibroblasts to differentiate into myoblasts. It is involved in muscle cell differentiation, and is essential for repair of damaged tissue. It activates its own transcription which may stabilize commitment to myogenesis. |
UniProt Protein Details: | Protein type:DNA-binding; Transcription factor; RNA splicing Chromosomal Location of Human Ortholog: 11p15.4 Cellular Component: nucleoplasm; transcription factor complex; myofibril; cytoplasm; nuclear chromatin; nucleus Molecular Function:RNA polymerase II transcription factor activity, enhancer binding; protein binding; chromatin DNA binding; protein heterodimerization activity; ubiquitin protein ligase binding; transcription coactivator activity; transcription factor binding; nuclear hormone receptor binding Biological Process: transcription from RNA polymerase II promoter; muscle development; skeletal muscle development; skeletal muscle fiber adaptation; positive regulation of skeletal muscle regeneration; regulation of RNA splicing; myotube differentiation involved in skeletal muscle regeneration; muscle cell fate commitment; skeletal muscle fiber development; myotube cell development; cellular response to starvation; protein amino acid phosphorylation; positive regulation of myoblast differentiation; regulation of transcription from RNA polymerase II promoter; muscle cell differentiation; positive regulation of skeletal muscle fiber development; positive regulation of muscle cell differentiation; positive regulation of transcription from RNA polymerase II promoter; myoblast cell fate determination; regulation of alternative nuclear mRNA splicing, via spliceosome |
NCBI Summary: | This gene encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis. [provided by RefSeq, Jul 2008] |
UniProt Code: | P15172 |
NCBI GenInfo Identifier: | 209572729 |
NCBI Gene ID: | 4654 |
NCBI Accession: | P15172.3 |
UniProt Secondary Accession: | P15172,O75321, |
UniProt Related Accession: | P15172 |
Molecular Weight: | 320 |
NCBI Full Name: | Myoblast determination protein 1 |
NCBI Synonym Full Names: | myogenic differentiation 1 |
NCBI Official Symbol: | MYOD1 |
NCBI Official Synonym Symbols: | PUM; MYF3; MYOD; bHLHc1 |
NCBI Protein Information: | myoblast determination protein 1; myf-3; myogenic factor 3; class C basic helix-loop-helix protein 1 |
UniProt Protein Name: | Myoblast determination protein 1 |
UniProt Synonym Protein Names: | Class C basic helix-loop-helix protein 1; bHLHc1; Myogenic factor 3; Myf-3 |
Protein Family: | Myoblast determination protein |
UniProt Gene Name: | MYOD1 |
UniProt Entry Name: | MYOD1_HUMAN |