Anti-MonoMethyl-Histone H3-R2 Antibody (CAB19645)
- SKU:
- CAB19645
- Product type:
- Antibody
- Application:
- WB
- Application:
- IP
- Application:
- ChIP
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
抗体名: | Anti-MonoMethyl-Histone H3-R2 Antibody |
抗体コード: | CAB19645 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IP ChIP |
反応性: | Human, Rat |
宿主種: | Rabbit |
免疫原: | A synthesized peptide derived from human Histone H3 (mono methyl R2). |
申し込み: | WB IP ChIP |
推奨希釈: | WB 1:500 - 1:2000 ChIP 1:20 - 1:100 |
反応性: | Human, Rat |
ポジティブサンプル: | HeLa, C6 |
免疫原: | A synthesized peptide derived from human Histone H3 (mono methyl R2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 8290/8350 |
Uniprot: | Q16695/P68431 |
セルラーロケーション: | |
計算された分子量: | 15kDa |
観察された分子量: | 17KDa |
同義語: | H3/A, H3C2, H3C3, H3C4, H3C6, H3C7, H3C8, H3FA, H3C10, H3C11, H3C12, HIST1H3A |
バックグラウンド: | This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. |