Anti-GAPDHS Antibody (CAB10471)
- SKU:
- CAB10471
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-GAPDHS Antibody |
抗体コード: | CAB10471 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 179-408 of human GAPDHS (NP_055179.1). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HT-1080, U-251MG, SW620, MCF-7, Mouse liver, Rat testis |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 179-408 of human GAPDHS (NP_055179.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | ASDH ISAG AQRV VISA PSPD APMF VMGV NEND YNPG SMNI VSNA SCTT NCLA PLAK VIHE RFGI VEGL MTTV HSYT ATQK TVDG PSRK AWRD GRGA HQNI IPAS TGAA KAVT KVIP ELKG KLTG MAFR VPTP DVSV VDLT CRLA QPAP YSAI KEAV KAAA KGPM AGIL AYTE DEVV STDF LGDT HSSI FDAK AGIA LNDN FVKL ISWY DNEY GYSH RVVD LLRY MFSR DK |
遺伝子ID: | 26330 |
Uniprot: | O14556 |
セルラーロケーション: | Cytoplasm |
計算された分子量: | 44kDa |
観察された分子量: | 60kDa |
同義語: | GAPDHS, GAPD2, GAPDH-2, GAPDS, HEL-S-278, HSD-35 |
バックグラウンド: | This gene encodes a protein belonging to the glyceraldehyde-3-phosphate dehydrogenase family of enzymes that play an important role in carbohydrate metabolism. Like its somatic cell counterpart, this sperm-specific enzyme functions in a nicotinamide adenine dinucleotide-dependent manner to remove hydrogen and add phosphate to glyceraldehyde 3-phosphate to form 1, 3-diphosphoglycerate. During spermiogenesis, this enzyme may play an important role in regulating the switch between different energy-producing pathways, and it is required for sperm motility and male fertility. |
UniProt Protein Function: | GAPDH-2: May play an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the spermatozoon. Required for sperm motility and male fertility. Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. |
UniProt Protein Details: | Protein type:EC 1.2.1.12; Oxidoreductase Chromosomal Location of Human Ortholog: 19q13.12 Cellular Component: cytosol; nucleus Molecular Function:glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity; protein binding Biological Process: gluconeogenesis; positive regulation of glycolysis; sperm motility |
NCBI Summary: | This gene encodes a protein belonging to the glyceraldehyde-3-phosphate dehydrogenase family of enzymes that play an important role in carbohydrate metabolism. Like its somatic cell counterpart, this sperm-specific enzyme functions in a nicotinamide adenine dinucleotide-dependent manner to remove hydrogen and add phosphate to glyceraldehyde 3-phosphate to form 1,3-diphosphoglycerate. During spermiogenesis, this enzyme may play an important role in regulating the switch between different energy-producing pathways, and it is required for sperm motility and male fertility. [provided by RefSeq, Jul 2008] |
UniProt Code: | O14556 |
NCBI GenInfo Identifier: | 6226817 |
NCBI Gene ID: | 26330 |
NCBI Accession: | O14556.2 |
UniProt Secondary Accession: | O14556,O60823, Q6JTT9, Q9HCU6, B2RC82, |
UniProt Related Accession: | O14556 |
Molecular Weight: | 44,501 Da |
NCBI Full Name: | Glyceraldehyde-3-phosphate dehydrogenase, testis-specific |
NCBI Synonym Full Names: | glyceraldehyde-3-phosphate dehydrogenase, spermatogenic |
NCBI Official Symbol: | GAPDHS |
NCBI Official Synonym Symbols: | GAPD2; GAPDS; HSD-35; GAPDH-2; HEL-S-278 |
NCBI Protein Information: | glyceraldehyde-3-phosphate dehydrogenase, testis-specific |
UniProt Protein Name: | Glyceraldehyde-3-phosphate dehydrogenase, testis-specific |
UniProt Synonym Protein Names: | Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2; GAPDH-2; Spermatogenic glyceraldehyde-3-phosphate dehydrogenase |
Protein Family: | Glyceraldehyde-3-phosphate dehydrogenase |
UniProt Gene Name: | GAPDHS |
UniProt Entry Name: | G3PT_HUMAN |
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