Anti-ECH1 Antibody (CAB12944)
- SKU:
- CAB12944
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-ECH1 Antibody |
抗体コード: | CAB12944 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-328 of human ECH1 (NP_001389.2). |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | A375, BxPC-3, HepG2, Jurkat, MCF7, K-562, Mouse testis, Rat liver |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-328 of human ECH1 (NP_001389.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MAAG IVAS RRLR DLLT RRLT GSNY PGLS ISLR LTGS SAQE EASG VALG EAPD HSYE SLRV TSAQ KHVL HVQL NRPN KRNA MNKV FWRE MVEC FNKI SRDA DCRA VVIS GAGK MFTA GIDL MDMA SDIL QPKG DDVA RISW YLRD IITR YQET FNVI ERCP KPVI AAVH GGCI GGGV DLVT ACDI RYCA QDAF FQVK EVDV GLAA DVGT LQRL PKVI GNQS LVNE LAFT ARKM MADE ALGS GLVS RVFP DKEV MLDA ALAL AAEI SSKS PVAV QSTK VNLL YSRD HSVA ESLN YVAS WNMS MLQT QDLV KSVQ ATTE NKEL KTVT FSKL |
遺伝子ID: | 1891 |
Uniprot: | Q13011 |
セルラーロケーション: | Mitochondrion, Peroxisome |
計算された分子量: | 35kDa |
観察された分子量: | 36kDa |
同義語: | ECH1, HPXEL |
バックグラウンド: | This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans, 5-cis-dienoyl-CoA to 2-trans, 4-trans-dienoyl-CoA, indicating that it is a delta3, 5-delta2, 4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators. |
UniProt Protein Function: | ECH1: Isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4- trans-dienoyl-CoA. Belongs to the enoyl-CoA hydratase/isomerase family. |
UniProt Protein Details: | Protein type:Mitochondrial; Isomerase; Amino Acid Metabolism - tyrosine; EC 5.3.3.- Chromosomal Location of Human Ortholog: 19q13.1 Cellular Component: membrane Molecular Function:protein binding; receptor binding |
NCBI Summary: | This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q13011 |
NCBI GenInfo Identifier: | 82654933 |
NCBI Gene ID: | 1891 |
NCBI Accession: | Q13011.2 |
UniProt Secondary Accession: | Q13011,Q8WVX0, Q96EZ9, A8K745, |
UniProt Related Accession: | Q13011 |
Molecular Weight: | 35,816 Da |
NCBI Full Name: | Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial |
NCBI Synonym Full Names: | enoyl-CoA hydratase 1 |
NCBI Official Symbol: | ECH1 |
NCBI Official Synonym Symbols: | HPXEL |
NCBI Protein Information: | delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial |
UniProt Protein Name: | Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial |
UniProt Gene Name: | ECH1 |
UniProt Entry Name: | ECH1_HUMAN |
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