Anti-DNA-RNA Hybrid Mouse Monoclonal Antibody (CAB19402)

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SKU:
CAB19402
Product type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Reactivity:
Other (Wide Range)
Host Species:
Mouse
Isotype:
IgG
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Description

system_update_altデータシートsystem_update_alt安全性データシート
抗体名:Anti-DNA-RNA Hybrid Mouse Monoclonal Antibody
抗体コード:CAB19402
抗体サイズ:20uL, 50 uL
申し込み:IF IP
反応性:Human, Mouse, Rat, Other (Wide Range)
宿主種:Mouse
免疫原:
申し込み:IF IP
推奨希釈:IF 1:50 - 1:500 IP 1:50 - 1:200
反応性:Human, Mouse, Rat, Other (Wide Range)
ポジティブサンプル:
免疫原:
精製方法:Affinity purification
ストレージバッファ:Store at -20°C. Avoid freeze / thaw cycles. Buffer: ddH?O with 50% glycerol.
アイソタイプ:IgG
順序:Email for sequence
遺伝子ID:
Uniprot:
セルラーロケーション:
計算された分子量:
観察された分子量:
Anti-DNA-RNA Hybrid Mouse Monoclonal Antibody (CAB19402)Immunofluorescence - DNA-RNA Hybrid Mouse mAb (CAB19402)
同義語:
バックグラウンド:The R-loop is a special chromosome structure that contains one strand of single-stranded DNA and another strand comprising a DNA:RNA hybrid. The distinct intermediate A/B conformation of the DNA:RNA hybrid makes it more stable than either dsDNA (double-stranded DNA, B form) or dsRNA (A form). R-loops normally form during transcription and play essential roles in key processes including chromatin modification, transcriptional regulation and termination, DNA replication and damage responses and genome stability. Most of the previous methods for genome-wide R-loop detection are based on immunoprecipitation using the monoclonal antibody S9.6 (which recognizes and binds to DNA:RNA hybrids in a non-sequence-specific manner) combined with high-throughput profiling such as tilling array hybridization and next-generation sequencing.
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