Anti-Cytokeratin-18 抗体 (CAB0389)

抗体名:	Anti-Cytokeratin-18 Mouse Monoclonal Antibody
抗体コード:	CAB0389
抗体サイズ:	100µL
申し込み:	WB ICC
反応性:	Human, Monkey
宿主種:	Mouse
免疫原:	Recombinant protein of human KRT18

申し込み:	WB ICC
推奨希釈:	WB 1:1000 - 1:4000 ICC 1:50 - 1:200
反応性:	Human, Monkey
ポジティブサンプル:	COS-7, HeLa, HT-29, LO2, A-549

免疫原:	Recombinant protein of human KRT18
精製方法:	Affinity purification
ストレージバッファ:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:	IgG
順序:	Email for sequence
遺伝子ID:	3875
Uniprot:	P05783
セルラーロケーション:	Cytoplasm, Nucleus, nucleolus, perinuclear region
計算された分子量:	48kDa
観察された分子量:	48kDa

同義語:

KRT18, CK-18, CYK18, K18, keratin 18

バックグラウンド:

KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.

UniProt Protein Function:	K18: a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 18 and its filament partner keratin 8 are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Defects are a cause of cryptogenic cirrhosis.
UniProt Protein Details:	Protein type:Nucleolus; Cytoskeletal Chromosomal Location of Human Ortholog: 12q13 Cellular Component: cytoplasm; intermediate filament; keratin filament; microtubule organizing center; nucleolus; perinuclear region of cytoplasm Molecular Function:protein binding; structural molecule activity Biological Process: anatomical structure morphogenesis; cell cycle; Golgi to plasma membrane CFTR protein transport; intermediate filament cytoskeleton organization and biogenesis; negative regulation of apoptosis; tumor necrosis factor-mediated signaling pathway; viral reproduction Disease: Cirrhosis, Familial
NCBI Summary:	KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:	P05783
NCBI GenInfo Identifier:	125083
NCBI Gene ID:	3875
NCBI Accession:	P05783.2
UniProt Secondary Accession:	P05783,Q53G38, Q5U0N8, Q9BW26,
UniProt Related Accession:	P05783
Molecular Weight:
NCBI Full Name:	Keratin, type I cytoskeletal 18
NCBI Synonym Full Names:	keratin 18
NCBI Official Symbol:	KRT18
NCBI Official Synonym Symbols:	K18; CK-18; CYK18
NCBI Protein Information:	keratin, type I cytoskeletal 18
UniProt Protein Name:	Keratin, type I cytoskeletal 18
UniProt Synonym Protein Names:	Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18; Keratin-18; K18
Protein Family:	Keratin
UniProt Gene Name:	KRT18
UniProt Entry Name:	K1C18_HUMAN

Anti-Cytokeratin-18 Mouse Monoclonal Antibody (CAB0389)

Western blot analysis of extracts of various cell lines, using Cytokeratin-18 antibody (CAB0389) at 1:2000 dilution. Secondary antibody: HRP Goat Anti-Mouse IgG (H+L) (CABS003) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s.

Antibodies	ELISA Kits
Anti-Cytokeratin-18 Antibody (CAB1022)	Human CK18 / KRT18 / Cytokeratin 18 ELISA Kit
Anti-KRT18 Antibody (CAB18010)[KO Validated]	Human CK-18/KRT18 (Cytokeratin 18) CLIA Kit (HUES01105)
KRT18 Antibody (PACO00114)	Human Keratin, type I cytoskeletal 18 (KRT18) ELISA Kit
Phospho-KRT18 (S33) Antibody (PACO00318)	Keratin 18 Colorimetric Cell-Based ELISA Kit
KRT18 Antibody (PACO00679)	Keratin 18 (Phospho-Ser33) Colorimetric Cell-Based ELISA Kit

Secondary Antibody

Anti-HRP Goat Anti-Mouse IgG (H+L) Antibody (CABS003)