Anti-CNN1 Antibody (RACO0159)
- SKU:
- RACO0159
- Product type:
- Recombinant Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Human
- Isotype:
- IgG
- Application:
- WB
- Application:
- ELISA
- Application:
- IHC
- Conjugation:
- Unconjugated
Frequently bought together:
Description
商品名: | CNN1 Antibody |
Product SKU: | RACO0159 |
サイズ: | 50ul |
宿主種: | Human |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | WB:1:500-1:5000, IHC:1:50-1:200 |
反応性: | Human, Mouse |
免疫原: | A synthesized peptide derived from human CNN1 |
憲法: | Liquid |
ストレージバッファ: | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
精製方法: | Affinity-chromatography |
抗体のクローン性: | Monoclonal |
アイソタイプ: | Rabbit IgG |
Conjugate: | Non-conjugated |
バックグラウンド: | Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity). |
シノニム: | Calponin-1, Basic calponin, Calponin H1, smooth muscle, CNN1 |
IHC image of RACO0159 diluted at 1:105 and staining in paraffin-embedded human heart tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. | |
Western Blot. Positive WB detected in 293 whole cell lysate Mouse lung tissue. All lanes CNN1 antibody at 1.05µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1:50000 dilution. Predicted band size: 34, 32 KDa. Observed band size: 34 KDa. |
UniProt Protein Function: | calponin 1: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. Belongs to the calponin family. |
UniProt Protein Details: | Protein type:Contractile; Motility/polarity/chemotaxis; Actin-binding; Myosin-binding Chromosomal Location of Human Ortholog: 19p13.2-p13.1 Cellular Component: cytoskeleton; focal adhesion Molecular Function:calmodulin binding; actin binding Biological Process: regulation of smooth muscle contraction; actomyosin structure organization and biogenesis |
UniProt Code: | P51911 |
NCBI GenInfo Identifier: | 2829431 |
NCBI Gene ID: | 1264 |
NCBI Accession: | P51911.2 |
UniProt Secondary Accession: | P51911,O00638, Q15416, Q8IY93, Q99438, B2R868, |
UniProt Related Accession: | P51911 |
Molecular Weight: | 33,170 Da |
NCBI Full Name: | Calponin-1 |
NCBI Synonym Full Names: | calponin 1, basic, smooth muscle |
NCBI Official Symbol: | CNN1 |
NCBI Official Synonym Symbols: | SMCC; Sm-Calp; HEL-S-14 |
NCBI Protein Information: | calponin-1; basic calponin; calponins, basic; calponin H1, smooth muscle; epididymis secretory protein Li 14 |
UniProt Protein Name: | Calponin-1 |
UniProt Synonym Protein Names: | Basic calponin; Calponin H1, smooth muscle |
Protein Family: | Calponin |
UniProt Gene Name: | CNN1 |
UniProt Entry Name: | CNN1_HUMAN |