Anti-CD160 antigen Antibody (CAB8189)
- SKU:
- CAB8189
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
抗体名: | CD160 Rabbit Polyclonal Antibody |
抗体コード: | CAB8189 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-181 of human CD160 (NP_008984.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | Jurkat, HT-29, U-937, Raji, Mouse spleen, Mouse small intestine, Mouse thymus, Rat thymus |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-181 of human CD160 (NP_008984.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MLLE PGRG CCAL AILL AIVD IQSG GCIN ITSS ASQE GTRL NLIC TVWH KKEE AEGF VVFL CKDR SGDC SPET SLKQ LRLK RDPG IDGV GEIS SQLM FTIS QVTP LHSG TYQC CARS QKSG IRLQ GHFF SILF TETG NYTV TGLK QRQH LEFS HNEG TLSS GFLQ EKVW VMLV TSLV ALQA L |
遺伝子ID: | 11126 |
Uniprot: | O95971 |
セルラーロケーション: | Cell membrane, GPI-anchor, Lipid-anchor |
計算された分子量: | 19kDa |
観察された分子量: | 20kDa |
同義語: | CD160, BY55, NK1, NK28 |
バックグラウンド: | CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. |
UniProt Protein Function: | Receptor showing broad specificity for both classical and non-classical MHC class I molecules. |
NCBI Summary: | CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. [provided by RefSeq, Jul 2008] |
UniProt Code: | O95971 |
NCBI GenInfo Identifier: | 17372903 |
NCBI Gene ID: | 11126 |
NCBI Accession: | O95971.1 |
UniProt Related Accession: | O95971 |
Molecular Weight: | 19,810 Da |
NCBI Full Name: | CD160 antigen |
NCBI Synonym Full Names: | CD160 molecule |
NCBI Official Symbol: | CD160 |
NCBI Official Synonym Symbols: | NK1; BY55; NK28 |
NCBI Protein Information: | CD160 antigen |
UniProt Protein Name: | CD160 antigen |
UniProt Synonym Protein Names: | Natural killer cell receptor BY55; CD_antigen: CD160 |
Protein Family: | CD160 antigen |
UniProt Gene Name: | CD160 |
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