Anti-AGO3 Antibody (RACO0138)
- SKU:
- RACO0138
- Product type:
- Recombinant Antibody
- Reactivity:
- Human
- Host Species:
- Human
- Isotype:
- IgG
- Application:
- ELISA
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| 商品名: | AGO3 Antibody |
| Product SKU: | RACO0138 |
| サイズ: | 50ul |
| 宿主種: | Human |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | A synthesized peptide derived from human AGO3 |
| 憲法: | Liquid |
| ストレージバッファ: | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 精製方法: | Affinity-chromatography |
| 抗体のクローン性: | Monoclonal |
| アイソタイプ: | Rabbit IgG |
| Conjugate: | Non-conjugated |
| バックグラウンド: | Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4. Possesses RNA slicer activity but only on select RNAs bearing 5'- and 3'-flanking sequences to the region of guide-target complementarity (PubMed:29040713). |
| シノニム: | Protein argonaute-3UniRule annotation, Argonaute RISC catalytic component 3, Eukaryotic translation initiation factor 2C 3UniRule annotation, AGO3, EIF2C3 |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9H9G7 |
| NCBI GenInfo Identifier: | 29294647 |
| NCBI Gene ID: | 192669 |
| NCBI Accession: | NP_079128.2 |
| UniProt Secondary Accession: | Q9H9G7,Q5TA55, Q9H1U6, B1ALI0 |
| UniProt Related Accession: | Q9H9G7 |
| Molecular Weight: | 97,360 Da |
| NCBI Full Name: | protein argonaute-3 isoform a |
| NCBI Synonym Full Names: | argonaute RISC catalytic component 3 |
| NCBI Official Symbol: | AGO3 |
| NCBI Official Synonym Symbols: | EIF2C3 |
| NCBI Protein Information: | protein argonaute-3; hAgo3; eIF2C 3; eIF-2C 3; argonaute3; argonaute 3; eukaryotic translation initiation factor 2C, 3 |
| UniProt Protein Name: | Protein argonaute-3 |
| UniProt Synonym Protein Names: | Argonaute RISC catalytic component 3; Eukaryotic translation initiation factor 2C 3; eIF-2C 3; eIF2C 3 |
| Protein Family: | Protein argonaute |
| UniProt Gene Name: | AGO3 |
| UniProt Entry Name: | AGO3_HUMAN |
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