Anti-14-3-3 epsilon Antibody (CAB4933)
- SKU:
- CAB4933
- Product type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- 14-3-3E
- Synonyms:
- HEL2
- Synonyms:
- KCIP-1
- Synonyms:
- MDCR
- Synonyms:
- MDS
Frequently bought together:
Description
抗体名: | 14-3-3 epsilon Rabbit mAb |
抗体コード: | CAB4933 |
サイズ: | 20uL, 50uL, 100uL |
同義語: | 14-3-3E, HEL2, KCIP-1, MDCR, MDS |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthesized peptide derived from human 14-3-3 epsilon |
申し込み: | WB |
推奨される希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HeLa, Mouse brain, Mouse kidney, Rat lung, Rat brain |
免疫原: | A synthesized peptide derived from human 14-3-3 epsilon |
精製方法: | Affinity purification |
保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 7531 |
Uniprot: | P62258 |
セルラーロケーション: | Cytoplasm, Melanosome |
計算された分子量: | 29kDa |
観察された分子量: | 28KDa |
UniProt Protein Function: | Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Positively regulates phosphorylated protein HSF1 nuclear export to the cytoplasm (PubMed:12917326). |
NCBI Summary: | This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008] |
UniProt Code: | P62258 |
NCBI GenInfo Identifier: | 51702210 |
NCBI Gene ID: | 7531 |
NCBI Accession: | P62258.1 |
UniProt Secondary Accession: | P62258,P29360, P42655, Q4VJB6, Q53XZ5, Q63631, Q7M4R4 B3KY71, D3DTH5, |
UniProt Related Accession: | P62258 |
Molecular Weight: | 26,504 Da |
NCBI Full Name: | 14-3-3 protein epsilon |
NCBI Synonym Full Names: | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon |
NCBI Official Symbol: | YWHAE |
NCBI Official Synonym Symbols: | MDS; HEL2; MDCR; KCIP-1; 14-3-3E |
NCBI Protein Information: | 14-3-3 protein epsilon |
UniProt Protein Name: | 14-3-3 protein epsilon |
Protein Family: | 14-3-3 protein |
UniProt Gene Name: | YWHAE |