UniProt Protein Function: | AMY1: Monomer. Belongs to the glycosyl hydrolase 13 family. |
UniProt Protein Details: | Protein type:Hydrolase; Carbohydrate Metabolism - starch and sucrose; Secreted; EC 3.2.1.1; Secreted, signal peptide Chromosomal Location of Human Ortholog: 1p21 Cellular Component: extracellular space Molecular Function:alpha-amylase activity; protein binding; metal ion binding Biological Process: carbohydrate metabolic process; digestion |
NCBI Summary: | Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the salivary gland. [provided by RefSeq, Jul 2008] |
UniProt Code: | P04745 |
NCBI GenInfo Identifier: | 1351933 |
NCBI Gene ID: | 277 |
NCBI Accession: | P04745.2 |
UniProt Secondary Accession: | P04745,Q13763, Q5T083, A6NJS5, A8K8H6, |
UniProt Related Accession: | P04745 |
Molecular Weight: | |
NCBI Full Name: | Alpha-amylase 1 |
NCBI Synonym Full Names: | amylase, alpha 1B (salivary) |
NCBI Official Symbol: | AMY1B |
NCBI Official Synonym Symbols: | AMY1 |
NCBI Protein Information: | alpha-amylase 1; glycogenase; salivary alpha-amylase; salivary amylase alpha 1B; amylase, salivary, alpha-1B; 1,4-alpha-D-glucan glucanohydrolase 1 |
UniProt Protein Name: | Alpha-amylase 1 |
UniProt Synonym Protein Names: | 1,4-alpha-D-glucan glucanohydrolase 1; Salivary alpha-amylase |
UniProt Gene Name: | AMY1A |
UniProt Entry Name: | AMY1_HUMAN |