AMD1 Antibody, HRP conjugated (PACO49391)
- SKU:
- PACO49391
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | AMD1 Antibody, HRP conjugated (PACO49391) |
抗体コード: | PACO49391 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human S-adenosylmethionine decarboxylase proenzyme protein (167-264AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels (By similarity). |
シノニム: | S-adenosylmethionine decarboxylase proenzyme (AdoMetDC) (SAMDC) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase α chain; S-adenosylmethionine decarboxylase β chain], AMD1, AMD |
UniProt Protein Function: | AMD1: an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Two alternatively spliced transcript variants that encode different proteins have been identified. Pseudogenes of this gene are found on chromosomes 5, 6, 10, X and Y.[provided by RefSeq, Jul 2010] |
UniProt Protein Details: | Protein type:Amino Acid Metabolism - arginine and proline; Lyase; Amino Acid Metabolism - cysteine and methionine; EC 4.1.1.50 Chromosomal Location of Human Ortholog: 6q21 Cellular Component: cytosol Molecular Function:adenosylmethionine decarboxylase activity Biological Process: S-adenosylmethioninamine biosynthetic process; spermidine biosynthetic process; spermine biosynthetic process; polyamine metabolic process |
NCBI Summary: | This gene encodes an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Multiple alternatively spliced transcript variants have been identified. Pseudogenes of this gene are found on chromosomes 5, 6, 10, X and Y. [provided by RefSeq, Dec 2013] |
UniProt Code: | P17707 |
NCBI GenInfo Identifier: | 116241324 |
NCBI Gene ID: | 262 |
NCBI Accession: | P17707.2 |
UniProt Secondary Accession: | P17707,Q5VXN4, Q5VXN6, Q9BWK4, E1P5F7, |
UniProt Related Accession: | P17707 |
Molecular Weight: | 21,301 Da |
NCBI Full Name: | S-adenosylmethionine decarboxylase proenzyme |
NCBI Synonym Full Names: | adenosylmethionine decarboxylase 1 |
NCBI Official Symbol: | AMD1 |
NCBI Official Synonym Symbols: | AMD; SAMDC; ADOMETDC |
NCBI Protein Information: | S-adenosylmethionine decarboxylase proenzyme; S-adenosylmethionine decarboxylase 1 |
UniProt Protein Name: | S-adenosylmethionine decarboxylase proenzyme |
Protein Family: | S-adenosylmethionine decarboxylase proenzyme |
UniProt Gene Name: | AMD1 |
UniProt Entry Name: | DCAM_HUMAN |