AIFM2 Antibody, HRP conjugated (PACO63224)
- SKU:
- PACO63224
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | AIFM2 Antibody, HRP conjugated (PACO63224) |
抗体コード: | PACO63224 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Apoptosis-inducing factor 2 protein (110-373AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Oxidoreductase, which may play a role in mediating a p53/TP53-dependent apoptosis response. Probable oxidoreductase that acts as a caspase-independent mitochondrial effector of apoptotic cell death. Binds to DNA in a sequence-independent manner. May contribute to genotoxin-induced growth arrest. |
シノニム: | Apoptosis-inducing factor 2 (EC 1) (Apoptosis-inducing factor homologous mitochondrion-associated inducer of death) (Apoptosis-inducing factor-like mitochondrion-associated inducer of death) (p53-responsive gene 3 protein), AIFM2, AMID PRG3 |
UniProt Protein Function: | AIFM2: Oxidoreductase, which may play a role in mediating a p53/TP53-dependent apoptosis response. Probable oxidoreductase that acts as a caspase-independent mitochondrial effector of apoptotic cell death. Binds to DNA in a sequence-independent manner. May contribute to genotoxin-induced growth arrest. Belongs to the FAD-dependent oxidoreductase family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Apoptosis; EC 1.-.-.-; Membrane protein, integral; Mitochondrial; Oxidoreductase Chromosomal Location of Human Ortholog: 10q22.1 Cellular Component: cytoplasm; cytosol; extracellular space; lipid particle; mitochondrial outer membrane; mitochondrion Molecular Function:DNA binding; electron-transferring-flavoprotein dehydrogenase activity; FAD binding Biological Process: apoptotic mitochondrial changes; positive regulation of apoptosis; regulation of apoptosis |
NCBI Summary: | This gene encodes a flavoprotein oxidoreductase that binds single stranded DNA and is thought to contribute to apoptosis in the presence of bacterial and viral DNA. The expression of this gene is also found to be induced by tumor suppressor protein p53 in colon cancer cells. [provided by RefSeq, Nov 2010] |
UniProt Code: | Q9BRQ8 |
NCBI GenInfo Identifier: | 74752283 |
NCBI Gene ID: | 84883 |
NCBI Accession: | Q9BRQ8.1 |
UniProt Secondary Accession: | Q9BRQ8,Q63Z39, B3KXI0, |
UniProt Related Accession: | Q9BRQ8 |
Molecular Weight: | 41kDa |
NCBI Full Name: | Apoptosis-inducing factor 2 |
NCBI Synonym Full Names: | apoptosis inducing factor, mitochondria associated 2 |
NCBI Official Symbol: | AIFM2 |
NCBI Official Synonym Symbols: | AMID; PRG3 |
NCBI Protein Information: | apoptosis-inducing factor 2 |
UniProt Protein Name: | Apoptosis-inducing factor 2 |
UniProt Synonym Protein Names: | Apoptosis-inducing factor homologous mitochondrion-associated inducer of death; Apoptosis-inducing factor-like mitochondrion-associated inducer of death; p53-responsive gene 3 protein |
Protein Family: | Apoptosis-inducing factor |
UniProt Gene Name: | AIFM2 |