ADH4 Antibody (PACO43434)
- SKU:
- PACO43434
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | ADH4 Antibody (PACO43434) |
抗体コード: | PACO43434 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Alcohol dehydrogenase 4 protein (1-380AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO43434 at dilution of 1:100. |
バックグラウンド: | This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes. |
シノニム: | Alcohol dehydrogenase 4 (EC 1.1.1.1) (Alcohol dehydrogenase class II pi chain), ADH4 |
UniProt Protein Function: | ADH4: class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes. [provided by RefSeq, Jul 2008] |
UniProt Protein Details: | Protein type:Cofactor and Vitamin Metabolism - retinol; Xenobiotic Metabolism - drug metabolism - cytochrome P450; EC 1.1.1.1; Xenobiotic Metabolism - metabolism by cytochrome P450; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Amino Acid Metabolism - tyrosine; Oxidoreductase; Lipid Metabolism - fatty acid Chromosomal Location of Human Ortholog: 4q22 Cellular Component: cytosol Molecular Function:zinc ion binding; NADPH:quinone reductase activity; alcohol dehydrogenase activity; all-trans retinal binding; alcohol dehydrogenase activity, zinc-dependent; ethanol binding; aldehyde reductase activity; benzaldehyde dehydrogenase activity; NAD binding; retinol binding; retinol dehydrogenase activity; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Biological Process: retinol metabolic process; xenobiotic metabolic process; alcohol metabolic process; alcohol catabolic process; aldehyde metabolic process; ethanol oxidation; retinoid metabolic process |
NCBI Summary: | This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes. [provided by RefSeq, Jul 2008] |
UniProt Code: | P08319 |
NCBI GenInfo Identifier: | 308153684 |
NCBI Gene ID: | 127 |
NCBI Accession: | P08319.5 |
UniProt Secondary Accession: | P08319,Q8TCD7, A8K470, B4DIE7, C9J4A9, |
UniProt Related Accession: | P08319 |
Molecular Weight: | 380 |
NCBI Full Name: | Alcohol dehydrogenase 4 |
NCBI Synonym Full Names: | alcohol dehydrogenase 4 (class II), pi polypeptide |
NCBI Official Symbol: | ADH4 |
NCBI Official Synonym Symbols: | ADH-2; HEL-S-4 |
NCBI Protein Information: | alcohol dehydrogenase 4; aldehyde reductase; epididymis secretory protein Li 4; alcohol dehydrogenase class II pi chain |
UniProt Protein Name: | Alcohol dehydrogenase 4 |
UniProt Synonym Protein Names: | Alcohol dehydrogenase class II pi chain |
Protein Family: | Alcohol dehydrogenase |
UniProt Gene Name: | ADH4 |
UniProt Entry Name: | ADH4_HUMAN |