UniProt Protein Function: | Orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. May play a role in regulatory T-cells (Treg) development. |
NCBI Summary: | This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] |
UniProt Code: | Q14246 |
NCBI GenInfo Identifier: | 372266078 |
NCBI Gene ID: | 2015 |
NCBI Accession: | NP_001243181.1 |
UniProt Secondary Accession: | Q14246,Q2I7G5, Q6ZMN0, Q8NGA7, A6NHV2, B7Z486, B7Z489 E7EPX9, E9PD45, H9KV79, |
UniProt Related Accession: | Q14246 |
Molecular Weight: | 102 kDa |
NCBI Full Name: | adhesion G protein-coupled receptor E1 isoform 2 |
NCBI Synonym Full Names: | adhesion G protein-coupled receptor E1 |
NCBI Official Symbol: | ADGRE1 |
NCBI Official Synonym Symbols: | EMR1; TM7LN3 |
NCBI Protein Information: | adhesion G protein-coupled receptor E1 |
UniProt Protein Name: | Adhesion G protein-coupled receptor E1 |
UniProt Synonym Protein Names: | EGF-like module receptor 1; EGF-like module-containing mucin-like hormone receptor-like 1; EMR1 hormone receptor |
UniProt Gene Name: | ADGRE1 |