ADCYAP1R1 Antibody (PACO18799)
- SKU:
- PACO18799
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | ADCYAP1R1 Antibody (PACO18799) |
抗体コード: | PACO18799 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:50-1:200 |
反応性: | Human, Mouse |
免疫原: | Synthetic peptide of human ADCYAP1R1 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO18799(ADCYAP1R1 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Hela cells, Mouse stomach tissue, Mouse brain tissue, Primary antibody: PACO18799(ADCYAP1R1 Antibody) at dilution 1/2000, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes. | |
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using PACO18799(ADCYAP1R1 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. |
シノニム: | Adenylate cyclase activating polypeptide 1 (pituitary) receptor type I |
UniProt Protein Function: | ADCYAP1R1: This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract. Belongs to the G-protein coupled receptor 2 family. 5 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 2; Membrane protein, integral Chromosomal Location of Human Ortholog: 7p14 Cellular Component: neuron projection; cell surface; tight junction; rough endoplasmic reticulum; integral to plasma membrane; plasma membrane; caveola; receptor complex; endosome Molecular Function:ADP-ribosylation factor binding; neuropeptide binding; vasoactive intestinal polypeptide receptor activity; protein binding; receptor activity; adenylate cyclase binding Biological Process: response to drug; G-protein coupled receptor protein signaling pathway; development of primary female sexual characteristics; cAMP-mediated signaling; response to ethanol; cell surface receptor linked signal transduction; nerve growth factor receptor signaling pathway; phospholipase C activation; adenylate cyclase activation; spermatogenesis; cell differentiation; multicellular organismal response to stress; response to estradiol stimulus; transmembrane receptor protein tyrosine kinase signaling pathway |
NCBI Summary: | This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2010] |
UniProt Code: | P41586 |
NCBI GenInfo Identifier: | 1171986 |
NCBI Gene ID: | 117 |
NCBI Accession: | P41586.1 |
UniProt Related Accession: | P41586 |
Molecular Weight: | |
NCBI Full Name: | Pituitary adenylate cyclase-activating polypeptide type I receptor |
NCBI Synonym Full Names: | ADCYAP receptor type I |
NCBI Official Symbol: | ADCYAP1R1 |
NCBI Official Synonym Symbols: | PAC1; PAC1R; PACAPR; PACAPRI |
NCBI Protein Information: | pituitary adenylate cyclase-activating polypeptide type I receptor |
UniProt Protein Name: | Pituitary adenylate cyclase-activating polypeptide type I receptor |
Protein Family: | PACRG-like protein |
UniProt Gene Name: | ADCYAP1R1 |
UniProt Entry Name: | PACR_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |