ADAMTS7 Antibody (PACO42446)
- SKU:
- PACO42446
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ADAMTS7 Antibody (PACO42446) |
抗体コード: | PACO42446 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
反応性: | Human, Mouse |
免疫原: | Recombinant Human A disintegrin and metalloproteinase with thrombospondin motifs 7 protein (242-593AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: ADAMTS7 antibody at 2µg/ml + Mouse brain tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 184 kDa. Observed band size: 184 kDa. | |
Immunohistochemistry of paraffin-embedded human brain tissue using PACO42446 at dilution of 1:100. |
バックグラウンド: | Metalloprotease that may play a role in the degradation of COMP. |
シノニム: | A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS 7) (ADAM-TS7) (ADAMTS-7) (EC 3.4.24.-) (COMPase), ADAMTS7 |
UniProt Protein Function: | ADAMTS7: Metalloprotease that may play a role in the degradation of COMP. |
UniProt Protein Details: | Protein type:Cell surface; EC 3.4.24.-; Motility/polarity/chemotaxis; Protease; Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 15q25.1 Cellular Component: endoplasmic reticulum lumen Molecular Function:metalloendopeptidase activity; metallopeptidase activity; protein binding Biological Process: negative regulation of chondrocyte differentiation; proteolysis involved in cellular protein catabolic process |
NCBI Summary: | The protein encoded by this gene is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and may regulate vascular smooth muscle cell (VSMC) migration. Mutations in this gene may be associated with susceptibility to coronary artery disease. [provided by RefSeq, Feb 2016] |
UniProt Code: | Q9UKP4 |
NCBI GenInfo Identifier: | 38683827 |
NCBI Gene ID: | 11173 |
NCBI Accession: | NP_055087.2 |
UniProt Secondary Accession: | Q9UKP4,Q14F51, Q6P7J9, |
UniProt Related Accession: | Q9UKP4 |
Molecular Weight: | 55.12kD |
NCBI Full Name: | A disintegrin and metalloproteinase with thrombospondin motifs 7 preproprotein |
NCBI Synonym Full Names: | ADAM metallopeptidase with thrombospondin type 1 motif 7 |
NCBI Official Symbol: | ADAMTS7 |
NCBI Official Synonym Symbols: | ADAM-TS7; ADAMTS-7; ADAM-TS 7 |
NCBI Protein Information: | A disintegrin and metalloproteinase with thrombospondin motifs 7 |
UniProt Protein Name: | A disintegrin and metalloproteinase with thrombospondin motifs 7 |
UniProt Synonym Protein Names: | COMPase |
Protein Family: | A disintegrin and metalloproteinase with thrombospondin motifs |
UniProt Gene Name: | ADAMTS7 |
Antibodies | ELISA Kits |
Anti-ADAMTS7 Antibody (CAB17093) | Human ADAMTS7 ELISA Kit |
ADAMTS7 Antibody (PACO03385) | Human A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAMTS7) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-HRP-conjugated Beta Actin Antibody (CABC028) |