ACO2 Antibody (PACO55262)
- SKU:
- PACO55262
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ACO2 Antibody (PACO55262) |
抗体コード: | PACO55262 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
反応性: | Human, Rat, Mouse |
免疫原: | Recombinant Human Aconitate hydratase, mitochondrial protein (452-676AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: Rat heart tissue, Mouse heart tissue. All lanes: ACO2 antibody at 2.5µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 86 kDa. Observed band size: 86 kDa. | |
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO55262 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human lung cancer using PACO55262 at dilution of 1:100. |
バックグラウンド: | Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. |
シノニム: | Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase), ACO2 |
UniProt Protein Function: | ACO2: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. Monomer. Belongs to the aconitase/IPM isomerase family. |
UniProt Protein Details: | Protein type:Lyase; EC 4.2.1.3; Carbohydrate Metabolism - glyoxylate and dicarboxylate; Carbohydrate Metabolism - citrate (TCA) cycle; Mitochondrial Chromosomal Location of Human Ortholog: 22q13.2 Cellular Component: mitochondrion; mitochondrial matrix; nucleus Molecular Function:iron ion binding; 4 iron, 4 sulfur cluster binding; aconitate hydratase activity; 3 iron, 4 sulfur cluster binding Biological Process: isocitrate metabolic process; cellular metabolic process; generation of precursor metabolites and energy; tricarboxylic acid cycle; citrate metabolic process Disease: Infantile Cerebellar-retinal Degeneration; Optic Atrophy 8 |
NCBI Summary: | The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q99798 |
NCBI GenInfo Identifier: | 6686275 |
NCBI Gene ID: | 50 |
NCBI Accession: | Q99798.2 |
UniProt Related Accession: | Q99798 |
Molecular Weight: | |
NCBI Full Name: | Aconitate hydratase, mitochondrial |
NCBI Synonym Full Names: | aconitase 2 |
NCBI Official Symbol: | ACO2 |
NCBI Official Synonym Symbols: | ICRD; OCA8; OPA9; ACONM; HEL-S-284 |
NCBI Protein Information: | aconitate hydratase, mitochondrial |
UniProt Protein Name: | Aconitate hydratase, mitochondrial |
UniProt Synonym Protein Names: | Citrate hydro-lyase |
Protein Family: | Aconitate hydratase |
UniProt Gene Name: | ACO2 |
UniProt Entry Name: | ACON_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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