ACAT2 Antibody (PACO43408)
- SKU:
- PACO43408
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ACAT2 Antibody (PACO43408) |
抗体コード: | PACO43408 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Acetyl-CoA acetyltransferase, cytosolic protein (1-97AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human placenta tissue using PACO43408 at dilution of 1:100. |
バックグラウンド: | Acetyl-CoA acetyltransferase 2 (ACAT2), also known as cytosolic acetoacetyl-CoA thiolase, plays a role in regulating lipid metabolism (1). It catalyzes the synthesis of acetoacetyl-CoA from two acetyl-CoA molecules, which is later converted into steroids (2). |
シノニム: | Acetyl-CoA acetyltransferase, cytosolic (EC 2.3.1.9) (Acetyl-CoA transferase-like protein) (Cytosolic acetoacetyl-CoA thiolase), ACAT2, ACTL |
UniProt Protein Function: | ACAT2: The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation. [provided by RefSeq, Jul 2008] |
UniProt Protein Details: | Protein type:Carbohydrate Metabolism - butanoate; Lipid Metabolism - synthesis and degradation of ketone bodies; Carbohydrate Metabolism - pyruvate; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Amino Acid Metabolism - tryptophan; Acetyltransferase; Secondary Metabolites Metabolism - terpenoid backbone biosynthesis; Carbohydrate Metabolism - propanoate; EC 2.3.1.9; Lipid Metabolism - fatty acid; Amino Acid Metabolism - lysine degradation Chromosomal Location of Human Ortholog: 6q25.3 Cellular Component: nucleoplasm; cytoplasm; nucleolus; nucleus Molecular Function:acetyl-CoA C-acetyltransferase activity Biological Process: lipid metabolic process Disease: Acetyl-coa Acetyltransferase-2 Deficiency |
NCBI Summary: | The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014] |
UniProt Code: | Q9BWD1 |
NCBI GenInfo Identifier: | 52000838 |
NCBI Gene ID: | 39 |
NCBI Accession: | Q9BWD1.2 |
UniProt Related Accession: | Q9BWD1 |
Molecular Weight: | 41 kDa |
NCBI Full Name: | Acetyl-CoA acetyltransferase, cytosolic |
NCBI Synonym Full Names: | acetyl-CoA acetyltransferase 2 |
NCBI Official Symbol: | ACAT2 |
NCBI Protein Information: | acetyl-CoA acetyltransferase, cytosolic |
UniProt Protein Name: | Acetyl-CoA acetyltransferase, cytosolic |
UniProt Synonym Protein Names: | Acetyl-CoA transferase-like protein; Cytosolic acetoacetyl-CoA thiolase |
Protein Family: | Acetyl-CoA acetyltransferase |
UniProt Gene Name: | ACAT2 |
UniProt Entry Name: | THIC_HUMAN |
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