Anti-SULT1C2 Antibody (CAB8154)
- SKU:
- CAB8154
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | SULT1C2 Rabbit Polyclonal Antibody |
| 抗体コード: | CAB8154 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human SULT1C2 (NP_001047.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse |
| ポジティブサンプル: | Mouse liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human SULT1C2 (NP_001047.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MALT SDLG KQIK LKEV EGTL LQPA TVDN WSQI QSFE AKPD DLLI CTYP KAGT TWIQ EIVD MIEQ NGDV EKCQ RAII QHRH PFIE WARP PQPS GVEK AKAM PSPR ILKT HLST QLLP PSFW |
| 遺伝子ID: | 6819 |
| Uniprot: | O00338 |
| セルラーロケーション: | Cytoplasm |
| 計算された分子量: | 34kDa/35kDa |
| 観察された分子量: | 35kDa |
| 同義語: | SULT1C2, ST1C1, ST1C2, SULT1C1, humSULTC2 |
| バックグラウンド: | Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that belongs to the SULT1 subfamily, responsible for transferring a sulfo moiety from PAPS to phenol-containing compounds. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| UniProt Protein Function: | SULT1C1: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of drugs, xenobiotic compounds, hormones, and neurotransmitters. May be involved in the activation of carcinogenic hyroxylamines. Shows activity towards p-nitrophenol and N-hydroxy-2-acetylamino-fluorene (N-OH-2AAF). Belongs to the sulfotransferase 1 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Transferase; EC 2.8.2.- Chromosomal Location of Human Ortholog: 2q12.3 Cellular Component: cytoplasm; cytosol Molecular Function:aryl sulfotransferase activity; protein binding; sulfotransferase activity Biological Process: 3'-phosphoadenosine 5'-phosphosulfate metabolic process; amine metabolic process; sulfation |
| NCBI Summary: | Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that belongs to the SULT1 subfamily, responsible for transferring a sulfo moiety from PAPS to phenol-containing compounds. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O00338 |
| NCBI GenInfo Identifier: | 29029530 |
| NCBI Gene ID: | 6819 |
| NCBI Accession: | NP_789795 |
| UniProt Secondary Accession: | O00338,Q53SG4, B2R813, |
| UniProt Related Accession: | O00338 |
| Molecular Weight: | 35,868 Da |
| NCBI Full Name: | sulfotransferase 1C2 isoform b |
| NCBI Synonym Full Names: | sulfotransferase family 1C member 2 |
| NCBI Official Symbol: | SULT1C2 |
| NCBI Official Synonym Symbols: | ST1C1; ST1C2; SULT1C1; humSULTC2 |
| NCBI Protein Information: | sulfotransferase 1C2 |
| UniProt Protein Name: | Sulfotransferase 1C2 |
| UniProt Synonym Protein Names: | Sulfotransferase 1C1; SULT1C#1; humSULTC2 |
| Protein Family: | Sulfotransferase |
| UniProt Gene Name: | SULT1C2 |
| UniProt Entry Name: | ST1C2_HUMAN |
 | Western blot analysis of extracts of mouse liver, using SULT1C2 antibody (CAB8154) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 45s. |
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