Anti-KANSL1 Antibody (CAB10755)
- SKU:
- CAB10755
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-KANSL1 Antibody |
| 抗体コード: | CAB10755 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 806-1105 of human KANSL1 (NP_056258.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | 293T, U-87MG, A-549 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 806-1105 of human KANSL1 (NP_056258.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | SSSS YLAA THHP PHSP LVRQ LSTS SDSP APAS SSSQ VTAS TSQQ PVRR RRGE SSFD INNI VIPM SVAA TTRV EKLQ YKEI LTPS WREV DLQS LKGS PDEE NEEI EDLS DAAF AALH AKCE EMER ARWL WTTS VPPQ RRGS RSYR SSDG RTTP QLGS ANPS TPQP ASPD VSSS HSLS EYSH GQSP RSPI SPEL HSAP LTPV ARDT PRHL ASED TRCS TPEL GLDE QSVQ PWER RTFP LAHS PQAE CEDQ LDAQ ERAA RCTR RTSG SKTG RETE AAPT SPPI VPLK SRHL VAAA TAQR PTHR |
| 遺伝子ID: | 284058 |
| Uniprot: | Q7Z3B3 |
| セルラーロケーション: | Chromosome, Nucleus, centromere, kinetochore |
| 計算された分子量: | 41kDa/48kDa/121kDa |
| 観察された分子量: | 121kDa |
| 同義語: | KANSL1, CENP-36, KDVS, KIAA1267, MSL1v1, NSL1, hMSL1v1 |
| バックグラウンド: | This gene encodes a nuclear protein that is a subunit of two protein complexes involved with histone acetylation, the MLL1 complex and the NSL1 complex. The corresponding protein in Drosophila interacts with K(lysine) acetyltransferase 8, which is also a subunit of both the MLL1 and NSL1 complexes. |
| UniProt Protein Function: | KANSL1: As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 17q21.31 Cellular Component: histone acetyltransferase complex; nucleoplasm; nucleus Molecular Function:histone acetyltransferase activity (H4-K16 specific); protein binding Disease: Koolen-de Vries Syndrome |
| NCBI Summary: | This gene encodes a nuclear protein that is a subunit of two protein complexes involved with histone acetylation, the MLL1 complex and the NSL1 complex. The corresponding protein in Drosophila interacts with K(lysine) acetyltransferase 8, which is also a subunit of both the MLL1 and NSL1 complexes. [provided by RefSeq, Jun 2012] |
| UniProt Code: | Q7Z3B3 |
| NCBI GenInfo Identifier: | 334302834 |
| NCBI Gene ID: | 284058 |
| NCBI Accession: | Q7Z3B3.2 |
| UniProt Secondary Accession: | Q7Z3B3,Q6AW85, Q8IYH1, Q9BRH0, Q9NTE7, Q9UFT0, Q9ULF3 A8K5E4, B3KT49, I3L4J3, |
| UniProt Related Accession: | Q7Z3B3 |
| Molecular Weight: | 121kDa |
| NCBI Full Name: | KAT8 regulatory NSL complex subunit 1 |
| NCBI Synonym Full Names: | KAT8 regulatory NSL complex subunit 1 |
| NCBI Official Symbol: | KANSL1 |
| NCBI Official Synonym Symbols: | KDVS; NSL1; MSL1v1; CENP-36; hMSL1v1; KIAA1267 |
| NCBI Protein Information: | KAT8 regulatory NSL complex subunit 1 |
| UniProt Protein Name: | KAT8 regulatory NSL complex subunit 1 |
| UniProt Synonym Protein Names: | MLL1/MLL complex subunit KANSL1; MSL1 homolog 1; hMSL1v1; NSL complex protein NSL1; Non-specific lethal 1 homolog |
| Protein Family: | KAT8 regulatory NSL complex |
| UniProt Gene Name: | KANSL1 |
 | Western blot analysis of extracts of various cell lines, using KANSL1 antibody (CAB10755) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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