Anti-COL12A1 Antibody (CAB17462)
- SKU:
- CAB17462
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
抗体名: | Anti-COL12A1 Antibody |
抗体コード: | CAB17462 |
抗体サイズ: | 20uL, 50 uL |
申し込み: | IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-270 of human COL12A1 (NP_004361.3). |
申し込み: | IF |
推奨希釈: | IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-270 of human COL12A1 (NP_004361.3). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | EVDP PSDL NFKI IDEN TVHM SWAK PVDP IVGY RITV DPTT DGPT KEFT LSAS TTET LLSE LVPE TEYV VTIT SYDE VEES VPVI GQLT IQTG SSTK PVEK KPGK TEIQ KCSV SAWT DLVF LVDG SWSV GRNN FKYI LDFI AALV SAFD IGEE KTRV GVVQ YSSD TRTE FNLN QYYQ RDEL LAAI KKIP YKGG NTMT GDAI DYLV KNTF TESA GARV GFPK VAII ITDG KSQD EVEI PARE LRNV GVE |
遺伝子ID: | 1303 |
Uniprot: | Q99715 |
セルラーロケーション: | |
計算された分子量: | |
観察された分子量: | Refer to figures |
同義語: | BA209D8.1, BTHLM2, COL12A1L, DJ234P15.1, UCMD2, COL12A1 |
バックグラウンド: | This gene encodes the alpha chain of type XII collagen, a member of the FACIT (fibril-associated collagens with interrupted triple helices) collagen family. Type XII collagen is a homotrimer found in association with type I collagen, an association that is thought to modify the interactions between collagen I fibrils and the surrounding matrix. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
UniProt Protein Function: | COL12A1: Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix. Belongs to the fibril-associated collagens with interrupted helices (FACIT) family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Extracellular matrix; Secreted Chromosomal Location of Human Ortholog: 6q12-q13 Cellular Component: collagen type XII; extracellular matrix; extracellular space; endoplasmic reticulum lumen; extracellular region; vesicle Molecular Function:extracellular matrix structural constituent conferring tensile strength Biological Process: collagen catabolic process; extracellular matrix disassembly; extracellular matrix organization and biogenesis; collagen fibril organization; cell adhesion; skeletal development Disease: Ullrich Congenital Muscular Dystrophy 2; Bethlem Myopathy 2 |
NCBI Summary: | This gene encodes the alpha chain of type XII collagen, a member of the FACIT (fibril-associated collagens with interrupted triple helices) collagen family. Type XII collagen is a homotrimer found in association with type I collagen, an association that is thought to modify the interactions between collagen I fibrils and the surrounding matrix. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q99715 |
NCBI GenInfo Identifier: | 93141047 |
NCBI Gene ID: | 1303 |
NCBI Accession: | NP_004361.3 |
UniProt Related Accession: | Q99715 |
Molecular Weight: | Predicted Molecular Mass: 21.5kDaAccurate Molecular Mass: 29kDa |
NCBI Full Name: | collagen alpha-1(XII) chain long isoform |
NCBI Synonym Full Names: | collagen type XII alpha 1 chain |
NCBI Official Symbol: | COL12A1 |
NCBI Official Synonym Symbols: | UCMD2; BTHLM2; EDSMYP; COL12A1L; BA209D8.1; DJ234P15.1 |
NCBI Protein Information: | collagen alpha-1(XII) chain |
UniProt Protein Name: | Collagen alpha-1(XII) chain |
Protein Family: | Lantibiotic salivaricin |
UniProt Gene Name: | COL12A1 |
UniProt Entry Name: | COCA1_HUMAN |