Anti-SEMA3A 抗体 (CAB5700)

抗体名:	Anti-SEMA3A Antibody
抗体コード:	CAB5700
抗体サイズ:	20uL, 50uL, 100uL
申し込み:	WB
反応性:	Rat
宿主種:	Rabbit
免疫原:	Recombinant fusion protein containing a sequence corresponding to amino acids 20-270 of human SEMA3A (NP_006071.1).

申し込み:	WB
推奨希釈:	WB 1:500 - 1:2000
反応性:	Rat
ポジティブサンプル:	Rat brain

免疫原:	Recombinant fusion protein containing a sequence corresponding to amino acids 20-270 of human SEMA3A (NP_006071.1).
精製方法:	Affinity purification
ストレージバッファ:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:	IgG
順序:	ANYQ NGKN NVPR LKLS YKEM LESN NVIT FNGL ANSS SYHT FLLD EERS RLYV GAKD HIFS FDLV NIKD FQKI VWPV SYTR RDEC KWAG KDIL KECA NFIK VLKA YNQT HLYA CGTG AFHP ICTY IEIG HHPE DNIF KLEN SHFE NGRG KSPY DPKL LTAS LLID GELY SGTA ADFM GRDF AIFR TLGH HHPI RTEQ HDSR WLND PKFI SAHL ISES DNPE DDKV YFFF RENA IDGE HSGK ATHA RIGQ ICK
遺伝子ID:	10371
Uniprot:	Q14563
セルラーロケーション:	Secreted
計算された分子量:	88kDa
観察された分子量:	89KDa

同義語:

SEMA3A, COLL1, HH16, Hsema-I, Hsema-III, SEMA1, SEMAD, SEMAIII, SEMAL, SemD, coll-1

バックグラウンド:

This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.

UniProt Protein Function:	SEMA3A: Induces the collapse and paralysis of neuronal growth cones. Could serve as a ligand that guides specific growth cones by a motility-inhibiting mechanism. Binds to the complex neuropilin-1/plexin-1. Belongs to the semaphorin family.
UniProt Protein Details:	Protein type:Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide Chromosomal Location of Human Ortholog: 7p12.1 Cellular Component: axon; extracellular region; extracellular space Molecular Function:chemorepellent activity; semaphorin receptor binding Biological Process: axon extension involved in axon guidance; axon guidance; negative regulation of axon extension involved in axon guidance; nerve development; neural crest cell migration; neuron migration; olfactory bulb development; regulation of axon extension involved in axon guidance; sensory system development; sympathetic nervous system development Disease: Hypogonadotropic Hypogonadism 16 With Or Without Anosmia
NCBI Summary:	This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease. [provided by RefSeq, Jul 2008]
UniProt Code:	Q14563
NCBI GenInfo Identifier:	8134674
NCBI Gene ID:	10371
NCBI Accession:	Q14563.1
UniProt Related Accession:	Q14563
Molecular Weight:
NCBI Full Name:	Semaphorin-3A
NCBI Synonym Full Names:	semaphorin 3A
NCBI Official Symbol:	SEMA3A
NCBI Official Synonym Symbols:	HH16; SemD; COLL1; SEMA1; SEMAD; SEMAL; coll-1; Hsema-I; SEMAIII; Hsema-III
NCBI Protein Information:	semaphorin-3A
UniProt Protein Name:	Semaphorin-3A
UniProt Synonym Protein Names:	Semaphorin III; Sema III
Protein Family:	Semaphorin
UniProt Gene Name:	SEMA3A
UniProt Entry Name:	SEM3A_HUMAN

Western blot analysis of extracts of Rat brain, using SEMA3A antibody (CAB5700) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.

Antibodies	ELISA Kits
Anti-SEMA3A Antibody (CAB12967)	Human Semaphorin 3A / SEMA3A ELISA Kit
SEMA3A Antibody (PACO03339)	Human SEMA3A (Semaphorin 3A) CLIA Kit (HUES00730)
	Human SEMA3A (Semaphorin 3A) ELISA Kit (HUES02332)
	Human Semaphorin-3A (SEMA3A) ELISA Kit

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)