Anti-Phospho-PKC (pan) (beta-II Ser660) Antibody (CABP0495)

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SKU:
CABP0495
Product type:
Antibody
Application:
WB
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
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Description

system_update_altデータシートsystem_update_alt安全性データシート
抗体名:Anti-Phospho-PKC (pan) (beta-II Ser660) Antibody
抗体コード:CABP0495
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB
反応性:Human, Mouse, Rat
宿主種:Rabbit
免疫原:A phospho specific peptide corresponding to residues surrounding Ser660 of human PKC (pan) BetaII
申し込み:WB
推奨希釈:WB 1:500 - 1:2000
反応性:Human, Mouse, Rat
ポジティブサンプル:293T, 293T+PMA
免疫原:A phospho specific peptide corresponding to residues surrounding Ser660 of human PKC (pan) BetaII
精製方法:Affinity purification
ストレージバッファ:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:Email for sequence
遺伝子ID:5578/5579/5580/5581/5583/5588
Uniprot:P17252/P05771/Q05655/Q02156/P24723/Q04759
セルラーロケーション:
計算された分子量:59kDa/67kDa/74- 83kDa
観察された分子量:95kDa
Anti-Phospho-PKC (pan) (beta-II Ser660) Antibody (CABP0495)Western blot analysis of extracts of 293T cells, using Phospho-PKC (pan) (beta II Ser660) pAb (CABP0495) at 1:1000 dilution or PRKCQ antibody (CAB5834).293T cells were treated by PMA/TPA (200nM) for 30 minutes after serum-starvation overnight. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% BSA. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
同義語:PRKCA/PRKCB/PRKCD/PRKCE/PRKCH/PRKCQ
バックグラウンド:Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. [provided by RefSeq, Jul 2008]
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