Anti-Phospho-INSR-Y1189/Y1190 + IGF1R-Y1165/Y1166 Antibody (CABP1086)

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SKU:
CABP1086
Product type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
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Description

system_update_altデータシートsystem_update_alt安全性データシート
抗体名:Anti-Phospho-INSR-Y1189/Y1190 + IGF1R-Y1165/Y1166 Antibody
抗体コード:CABP1086
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB
反応性:Human, Mouse, Rat
宿主種:Rabbit
免疫原:A phospho specific peptide corresponding to residues surrounding Y1189/Y1190 of human INSR and Y1165/Y1166 of human IGF1R.
申し込み:WB
推奨希釈:WB 1:500 - 1:2000
反応性:Human, Mouse, Rat
ポジティブサンプル:293T
免疫原:A phospho specific peptide corresponding to residues surrounding Y1189/Y1190 of human INSR and Y1165/Y1166 of human IGF1R.
精製方法:Affinity purification
ストレージバッファ:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:Email for sequence
遺伝子ID:3480/3643
Uniprot:P08069/P06213
セルラーロケーション:
計算された分子量:154kDa/155kDa/156kDa
観察された分子量:100kDa
Anti-Phospho-INSR-Y1189/Y1190 + IGF1R-Y1165/Y1166 Antibody (CABP1086)Western blot - Phospho-INSR-Y1189/Y1190 + IGF1R-Y1165/Y1166 Rabbit pAb (CABP1086)
同義語:IGF1R/INSR
バックグラウンド:This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
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