Anti-Phospho-ERK3-S189 Antibody (CABP0051)

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SKU:
CABP0051
Product type:
Antibody
Application:
WB
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Cycle
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Description

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抗体名:Anti-Phospho-ERK3-S189 Antibody
抗体コード:CABP0051
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB
反応性:Human, Mouse, Rat
宿主種:Rabbit
免疫原:A synthetic phosphorylated peptide around S189 of human ERK3 (NP_002739.1).
申し込み:WB
推奨希釈:WB 1:500 - 1:2000
反応性:Human, Mouse, Rat
ポジティブサンプル:293
免疫原:A synthetic phosphorylated peptide around S189 of human ERK3 (NP_002739.1).
精製方法:Affinity purification
ストレージバッファ:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:HLSE G
遺伝子ID:5597
Uniprot:Q16659
セルラーロケーション:Cytoplasm, Nucleus
計算された分子量:82kDa
観察された分子量:120kDa
Anti-Phospho-ERK3-S189 Antibody (CABP0051)Western blot analysis of extracts of 293 cells, using Phospho-ERK3-S189 antibody (CABP0051) at 1:1000 dilution. 293 cells were treated by PMA/TPA (200nM) for 30 minutes after serum-starvation overnight. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% BSA.
同義語:MAPK6, ERK3, HsT17250, PRKM6, p97MAPK
バックグラウンド:The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters.
UniProt Protein Function:ERK3: a protein kinase of the MAPK family. Plays a critical role in the regulation of cell growth and differentiation. Localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters.
UniProt Protein Details:

Protein type:Protein kinase, Ser/Thr (non-receptor); Protein kinase, CMGC; Kinase, protein; EC 2.7.11.24; CMGC group; MAPK family; MAPK/ERK subfamily; ERK subfamily

Chromosomal Location of Human Ortholog: 15q21

Cellular Component: cytoplasm; cytosol; nucleoplasm; nucleus

Molecular Function:MAP kinase activity; protein binding; protein serine/threonine kinase activity

Biological Process: protein amino acid phosphorylation; signal transduction

NCBI Summary:The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. [provided by RefSeq, Jul 2008]
UniProt Code:Q16659
NCBI GenInfo Identifier:2499596
NCBI Gene ID:5597
NCBI Accession:Q16659.1
UniProt Secondary Accession:Q16659,Q68DH4, Q8IYN8, B2R945, B5BU65,
UniProt Related Accession:Q16659
Molecular Weight:82,681 Da
NCBI Full Name:Mitogen-activated protein kinase 6
NCBI Synonym Full Names:mitogen-activated protein kinase 6
NCBI Official Symbol:MAPK6  
NCBI Official Synonym Symbols:ERK3; PRKM6; p97MAPK; HsT17250  
NCBI Protein Information:mitogen-activated protein kinase 6
UniProt Protein Name:Mitogen-activated protein kinase 6
UniProt Synonym Protein Names:Extracellular signal-regulated kinase 3; ERK-3; MAP kinase isoform p97; p97-MAPK
UniProt Gene Name:MAPK6  
UniProt Entry Name:MK06_HUMAN
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