Anti-Phospho-Ephrin-B2-Y316 Antibody (CABP0338)

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SKU:
CABP0338
Product type:
Antibody
Application:
WB
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cardiovascular
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Description

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抗体名:Anti-Phospho-Ephrin-B2-Y316 Antibody
抗体コード:CABP0338
抗体サイズ:100 uL
申し込み:WB
反応性:Human, Mouse
宿主種:Rabbit
免疫原:A phospho specific peptide corresponding to residues surrounding Y316 of human EFNB2
申し込み:WB
推奨希釈:WB 1:500 - 1:2000
反応性:Human, Mouse
ポジティブサンプル:HT-29, HT-29+UV
免疫原:A phospho specific peptide corresponding to residues surrounding Y316 of human EFNB2
精製方法:Affinity purification
ストレージバッファ:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:Email for sequence
遺伝子ID:1948
Uniprot:P52799
セルラーロケーション:Membrane, Single-pass type I membrane protein
計算された分子量:36kDa
観察された分子量:55kDa
Anti-Phospho-Ephrin-B2-Y316 Antibody (CABP0338)Western blot analysis of extracts from HT29 cells, using Phospho-EFNB2-Y316 antibody (CABP0338). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% BSA.
同義語:EFNB2, EPLG5, HTKL, Htk-L, LERK5, ephrin-B2
バックグラウンド:This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors.
UniProt Protein Function:EFNB2: a type I membrane protein of the ephrin family. A ligand of Eph-related receptor tyrosine kinases EphA3 and EphB4. Ephrins and ephrin receptors mediate numerous developmental processes, particularly in the nervous system. Ephrin-B2 is implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. May play a role in constraining the orientation of longitudinally projecting axons
UniProt Protein Details:

Protein type:Ligand, receptor tyrosine kinase; Membrane protein, integral

Chromosomal Location of Human Ortholog: 13q33

Cellular Component: focal adhesion; integral to plasma membrane; plasma membrane

Molecular Function:protein binding; ephrin receptor binding

Biological Process: axon guidance; organ morphogenesis; anatomical structure morphogenesis; regulation of chemotaxis; viral reproduction; cell-cell signaling; cell migration during sprouting angiogenesis; ephrin receptor signaling pathway; cell adhesion; lymph vessel development

NCBI Summary:This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors. [provided by RefSeq, Jul 2008]
UniProt Code:P52799
NCBI GenInfo Identifier:1706673
NCBI Gene ID:1948
NCBI Accession:P52799.1
UniProt Secondary Accession:P52799,Q5JV56,
UniProt Related Accession:P52799
Molecular Weight:333
NCBI Full Name:Ephrin-B2
NCBI Synonym Full Names:ephrin-B2
NCBI Official Symbol:EFNB2  
NCBI Official Synonym Symbols:HTKL; EPLG5; Htk-L; LERK5  
NCBI Protein Information:ephrin-B2; LERK-5; HTK ligand; ligand of eph-related kinase 5; eph-related receptor tyrosine kinase ligand 5
UniProt Protein Name:Ephrin-B2
UniProt Synonym Protein Names:EPH-related receptor tyrosine kinase ligand 5; LERK-5; HTK ligand; HTK-L
Protein Family:Ephrin
UniProt Gene Name:EFNB2  
UniProt Entry Name:EFNB2_HUMAN
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